Protein Alignment CTNND2 and VAC8

DIOPT Version :9

• Sequence 1: XP_005248308.1
• Gene: CTNND2 / 1501
• HGNCID: 2516
• Length: 1250
• Species: Homo sapiens
• Sequence 2: NP_010903.3
• Gene: VAC8 / 856702
• SGDID: S000000739
• Length: 578
• Species: Saccharomyces cerevisiae
• Alignment Length: 452
• Identity: 97/452 - (21%)
• Similarity: 176/452 - (38%)
• Gaps: 135/452 - (29%)

Human   565 SVQSNAAAYLQHLCFGD--NKIKAEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDD 627
            ::|.:||     |.|.:  .|...::.|: .::.::.||..:..::..:||.||.||.   .|::
Yeast    62 NLQRSAA-----LAFAEITEKYVRQVSRE-VLEPILILLQSQDPQIQVAACAALGNLA---VNNE 117

Human   628 NKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSG 692
            ||:.:...||:..|:..: ...::|::....|.:.||::.|..|..|       .|:..:||
Yeast   118 NKLLIVEMGGLEPLINQM-MGDNVEVQCNAVGCITNLATRDDNKHKI-------ATSGALIP--- 171

Human   693 WENSPLQDDRKIQLHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEID 757
              .:.|...:.|     :|.|||||.|.|::.: ||.|:.:     :....:.|:.|.|.|::.|
Yeast   172 --LTKLAKSKHI-----RVQRNATGALLNMTHS-EENRKEL-----VNAGAVPVLVSLLSSTDPD 223

Human   758 SKTVENCVCILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKSQDQW 822
            .                        |:..|..|..:...|||              :||.:|.:
Yeast   224 V------------------------QYYCTTALSNIAVDEAN--------------RKKLAQTE- 249

Human   823 DGVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKGWAEDVAG 887
                                 |.:|...::|:...|:....: |..||:|||:.:
Yeast   250 ---------------------PRLVSKLVSLMDSPSSRVKCQ-ATLALRNLASDT---------- 282

Human   888 MAYALRSLPEGAPCLPQWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKE 952
             :|.|..:..|                   |||.||:|::.|:..:|.|....:||:::...|:.
Yeast   283 -SYQLEIVRAG-------------------GLPHLVKLIQSDSIPLVLASVACIRNISIHPLNEG 327

Human   953 LIGKYAMRDLVHRLPGGNNSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEK 1014
            ||........:.||....:|......|:|         ||..:...:.:|.|...::|.:||
Yeast   328 LIVDAGFLKPLVRLLDYKDSEEIQCHAVS---------TLRNLAASSEKNRKEFFESGAVEK 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTNND2	XP_005248308.1	ARM	544..666	CDD:237987	25/102 (25%)
		armadillo repeat	552..577	CDD:293788	3/11 (27%)
		armadillo repeat	585..621	CDD:293788	9/35 (26%)
		armadillo repeat	629..664	CDD:293788	6/34 (18%)
		armadillo repeat	671..722	CDD:293788	14/50 (28%)
		Arm	834..875	CDD:278915	9/40 (23%)
		armadillo repeat	838..875	CDD:293788	9/36 (25%)
		armadillo repeat	910..944	CDD:293788	10/33 (30%)
		ARM	911..1043	CDD:237987	26/104 (25%)
		armadillo repeat	951..997	CDD:293788	9/45 (20%)
		armadillo repeat	1003..1038	CDD:293788	4/12 (33%)
		CAF20	<1054..1113	CDD:293657
VAC8	NP_010903.3	SRP1	42..>358	CDD:227396	90/428 (21%)
		armadillo repeat	119..155	CDD:293788	8/36 (22%)
		armadillo repeat	160..194	CDD:293788	14/50 (28%)
		armadillo repeat	204..235	CDD:293788	8/59 (14%)
		armadillo repeat	242..280	CDD:293788	12/60 (20%)
		armadillo repeat	286..319	CDD:293788	12/51 (24%)
		armadillo repeat	326..361	CDD:293788	9/43 (21%)
		armadillo repeat	369..402	CDD:293788	4/12 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2332
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940