Protein Alignment CTNND2 and ctnnd2

DIOPT Version :10

• Sequence 1: XP_005248308.1
• Gene: CTNND2 / 1501
• HGNCID: 2516
• Length: 1250
• Species: Homo sapiens
• Sequence 2: XP_031759534.1
• Gene: ctnnd2 / 100127641
• XenbaseID: XB-GENE-5888637
• Length: 1325
• Species: Xenopus tropicalis
• Alignment Length: 1360
• Identity: 1102/1360 - (81%)
• Similarity: 1145/1360 - (84%)
• Gaps: 145/1360 - (10%)

Human     1 MFARKP-PGAAPLGAMPVPDQPSSASEKTSSLSPGLNTSNGDGSETETTSAILASVKEQELQFER 64
            |||:.| ..:.|.||||||||| |.|||||||||.||||||||||||||||||||||||||||||
 Frog     1 MFAKNPGESSTPSGAMPVPDQP-SCSEKTSSLSPILNTSNGDGSETETTSAILASVKEQELQFER 64

Human    65 LTRELEAERQIVASQLERCKLGSETGSMSSMSSAEEQFQWQSQDGQKDIEDELTTGLELVDSCIR 129
            ||||||||||||||||||||||||||||||:||.||||:||:|||||||||||||||||||||||
 Frog    65 LTRELEAERQIVASQLERCKLGSETGSMSSISSTEEQFRWQTQDGQKDIEDELTTGLELVDSCIR 129

Human   130 SLQESGILDPQDYSTGERPSLLSQSALQLNSKPEGSFQYPASYHSNQTLALGETTPSQLPARGTQ 194
            ||||||||||||||:.|||||||||||||||||||||||.:||||||||||||::..|.|:|..|
 Frog   130 SLQESGILDPQDYSSSERPSLLSQSALQLNSKPEGSFQYSSSYHSNQTLALGESSALQFPSRSNQ 194

Human   195 ARATGQSFSQGTTSRAGHLAGPEPAPP-PPPPPREPFAPSLGSAFHLPDAPPAAAAAALYYSSST 258
            ||:..||:||||||||.|.:|.||:.. .....||.|.||.||||||||   :..::.|||||||
 Frog   195 ARSAIQSYSQGTTSRAAHSSGSEPSQSHAASQSRESFVPSHGSAFHLPD---SQHSSTLYYSSST 256

Human   259 LPAPPRGGSPLAAPQGGSPTKLQRGGSAPEGATYA-APRGSSPKQSPSRLAKSYSTSSPINIVVS 322
            ||| .|..|||:..|.||||||||.|||.|...|: ..|.|||||||||||||||||||||||||
 Frog   257 LPA-QRVSSPLSMQQVGSPTKLQRVGSASESTGYSTTQRVSSPKQSPSRLAKSYSTSSPINIVVS 320

Human   323 SAGLSP--IRVTSPPTVQSTISSSPIHQLSSTIGTYATLSPTKRLVHASEQYSKHSQELYATATL 385
            ||||||  :|||||||:||.|||||:|.|||||||||||||||||||.|:||:||| ||||||||
 Frog   321 SAGLSPSSVRVTSPPTIQSNISSSPLHSLSSTIGTYATLSPTKRLVHTSDQYNKHS-ELYATATL 384

Human   386 QRPGSLAAGSRASYSSQHGHLGPELRALQSPEHHIDPIYEDRVYQKPPMRSLSQSQGDPLPPAHT 450
            ||||||||||||||:|||.|||.|:|:|||||||||||||||||||||||||||||||.|.||||
 Frog   385 QRPGSLAAGSRASYTSQHSHLGSEIRSLQSPEHHIDPIYEDRVYQKPPMRSLSQSQGDTLLPAHT 449

Human   451 GTYRTST--------------------------APSSPGVDSVPLQRTGSQHGPQNAAAATFQRA 489
            .:|||:|                          ||||||||||||||||||||.|| |..|||||
 Frog   450 SSYRTNTDTVPDFDPMSLIFKSVVPDFSVGDLRAPSSPGVDSVPLQRTGSQHGTQN-ATGTFQRA 513

Human   490 SYAAGPASNYADPYRQLQYCPSVESPYSKSGPALPPEGTLARSPSIDSIQKDPREFGWRDPELPE 554
            |||||||:|||||||||||||||:|||||||||:|||||||||||||||||||||||||||||||
 Frog   514 SYAAGPAANYADPYRQLQYCPSVDSPYSKSGPAIPPEGTLARSPSIDSIQKDPREFGWRDPELPE 578

Human   555 VIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNL 619
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   579 VIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNL 643

Human   620 VYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELV------------TGVLWNLSSCDALKM 672
            ||||||||||||||||||||||||||||||||||||||            |||||||||||||||
 Frog   644 VYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTACNTNWGVRIQTGVLWNLSSCDALKM 708

Human   673 PIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLRNVSSAGEEARRRMRECD 737
            ||||||||||||||||||||||||.||||||:|||||||||||||||||||||||||||||||||
 Frog   709 PIIQDALAVLTNAVIIPHSGWENSILQDDRKVQLHSSQVLRNATGCLRNVSSAGEEARRRMRECD 773

Human   738 GLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKD 802
            |||||||||||||||||:||||||||||||||||||||||||||||.|||||||||||||.||||
 Frog   774 GLTDALLYVIQSALGSSDIDSKTVENCVCILRNLSYRLAAETSQGQQMGTDELDGLLCGENNGKD 838

Human   803 AESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAA 867
            .|||||||||||||||||||||||||||||:||||||||||||||||||||||||||||||||||
 Frog   839 TESSGCWGKKKKKKKSQDQWDGVGPLPDCADPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAA 903

Human   868 GALQNLAAGSWKGWAEDVAGMAYALRSLPEGAPCLPQWSVYIRAAVRKEKGLPILVELLRIDNDR 932
            ||||||||||||                         |||||||||||||||||||||||:||||
 Frog   904 GALQNLAAGSWK-------------------------WSVYIRAAVRKEKGLPILVELLRVDNDR 943

Human   933 VVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNTASKAMSDDTVTAVCCTLHEVIT 997
            ||||||||||||||||||||||||||||||||||||||||||:||||||||||||:|||||||||
 Frog   944 VVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNSASKAMSDDTVTAICCTLHEVIT 1008

Human   998 KNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYRDLRSLYKK--------- 1053
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog  1009 KNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYRDLRSLYKKQDAPGLKVN 1073

Human  1054 ---------------------------------DGWSQYHFVASSSTIERDRQRPYSSSRTPSIS 1085
                                             ||||||||||||||||||||||||||||||||
 Frog  1074 EERGYTPTLQSEPDNALYTLTQGQATRNNSQIQDGWSQYHFVASSSTIERDRQRPYSSSRTPSIS 1138

Human  1086 PVRVSPNNRSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKDAMTAQNTGISTLYR 1150
            |||:|||||||||||||||||||||||||||..|||||:   |||||||||.|||||||.|||||
 Frog  1139 PVRMSPNNRSASAPASPREMISLKERKTDYESPGSNATF---KGEHTSRKDTMTAQNTGTSTLYR 1200

Human  1151 NSYGAPAEDIKHNQV-------------------------SAQPVPQEPSRKDYETYQPFQNSTR 1190
            ||||.||||||||||                         |.|||||:.|||||:||||||||||
 Frog  1201 NSYGTPAEDIKHNQVASIVLSLPEDRSRVGVSDPATSLNISTQPVPQDSSRKDYDTYQPFQNSTR 1265

Human  1191 NYDESFFEDQVHHRPPASEYTMHLGLKSTGNYVDFYSAARPYSELNYETSHYPASPDSWV 1250
            |||:||||||||||||||||.|||||||||||||||||||||||||||||||||||||||
 Frog  1266 NYDDSFFEDQVHHRPPASEYNMHLGLKSTGNYVDFYSAARPYSELNYETSHYPASPDSWV 1325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTNND2	XP_005248308.1	PLN03200	550..>723	CDD:215629	170/184 (92%)
		armadillo repeat	552..577	CDD:293788	24/24 (100%)
		ARM	581..621	CDD:214547	39/39 (100%)
		armadillo repeat	585..621	CDD:293788	35/35 (100%)
		ARM	625..666	CDD:214547	40/52 (77%)
		armadillo repeat	629..664	CDD:293788	34/46 (74%)
		armadillo repeat	671..722	CDD:293788	48/50 (96%)
		Arm	834..875	CDD:425727	40/40 (100%)
		armadillo repeat	838..875	CDD:293788	36/36 (100%)
		ARM	910..945	CDD:214547	33/34 (97%)
		armadillo repeat	910..944	CDD:293788	32/33 (97%)
		armadillo repeat	951..997	CDD:293788	43/45 (96%)
		ARM	999..1043	CDD:214547	43/43 (100%)
		armadillo repeat	1003..1038	CDD:293788	34/34 (100%)
ctnnd2	XP_031759534.1	DUF5585	183..548	CDD:465521	262/370 (71%)
		armadillo repeat	576..601	CDD:293788	24/24 (100%)
		ARM	605..645	CDD:214547	39/39 (100%)
		armadillo repeat	609..645	CDD:293788	35/35 (100%)
		Arm	649..702	CDD:425727	40/52 (77%)
		armadillo repeat	653..700	CDD:293788	34/46 (74%)
		armadillo repeat	715..758	CDD:293788	40/42 (95%)
		Arm	870..911	CDD:425727	40/40 (100%)
		armadillo repeat	874..911	CDD:293788	36/36 (100%)
		ARM	921..956	CDD:214547	33/34 (97%)
		armadillo repeat	921..955	CDD:293788	32/33 (97%)
		armadillo repeat	962..1008	CDD:293788	43/45 (96%)
		ARM	1010..1054	CDD:214547	43/43 (100%)
		armadillo repeat	1014..1049	CDD:293788	34/34 (100%)