Protein Alignment CTNND1 and Ctnnd1

DIOPT Version :10

• Sequence 1: NP_001078927.1
• Gene: CTNND1 / 1500
• HGNCID: 2515
• Length: 968
• Species: Homo sapiens
• Sequence 2: XP_006498688.1
• Gene: Ctnnd1 / 12388
• MGIID: 105100
• Length: 967
• Species: Mus musculus
• Alignment Length: 968
• Identity: 943/968 - (97%)
• Similarity: 952/968 - (98%)
• Gaps: 1/968 - (0%)

Human     1 MDDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTLTRRHQ 65
            ||||||||||||||||||||||||||||||||||||||||||||||||||||.||||||||||||
Mouse     1 MDDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANSLMANGTLTRRHQ 65

Human    66 NGRFVGDADLERQKFSDLKLNGPQDHSHLLYSTIPRMQEPGQIVETYTEEDPEGAMSVVSVETSD 130
            ||||||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||:|
Mouse    66 NGRFVGDADLERQKFSDLKLNGPQDHNHLLYSTIPRMQEPGQIVETYTEEDPEGAMSVVSVETTD 130

Human   131 DGTTRRTETTVKKVVKTVTTRTVQPVAMGPDGLPVDASSVSNNYIQTLGRDFRKNGNGGPGPYVG 195
            |||||||||||||||||:||||||||.|||||||||||:||||||||||||||||||||||||||
Mouse   131 DGTTRRTETTVKKVVKTMTTRTVQPVPMGPDGLPVDASAVSNNYIQTLGRDFRKNGNGGPGPYVG 195

Human   196 QAGTATLPRNFHYPPDGYSRHYEDGYPGGSDNYGSLSRVTRIEERYRPSMEGYRAPSRQDVYGPQ 260
            ||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||
Mouse   196 QAGTATLPRNFHYPPDGYGRHYEDGYPGGSDNYGSLSRVTRIEERYRPSMEGYRAPSRQDVYGPQ 260

Human   261 PQVRVGGSSVDLHRFHPEPYGLEDDQRSMGYDDLDYGMMSDYGTARRTGTPSDPRRRLRSYEDMI 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 PQVRVGGSSVDLHRFHPEPYGLEDDQRSMGYDDLDYGMMSDYGTARRTGTPSDPRRRLRSYEDMI 325

Human   326 GEEVPSDQYYWAPLAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYL 390
            |||||.|||||||||||||||||||||||||.|||.|||||||||||||||||||||||||||||
Mouse   326 GEEVPPDQYYWAPLAQHERGSLASLDSLRKGMPPPSNWRQPELPEVIAMLGFRLDAVKSNAAAYL 390

Human   391 QHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPA 455
            |||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||
Mouse   391 QHLCYRNDKVKTDVRKLKGIPILVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPA 455

Human   456 LVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRH 520
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   456 LVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRH 520

Human   521 IEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRN 585
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   521 IEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRN 585

Human   586 LSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKDEWFSRGKKPIEDPANDTVDFPKRT 650
            ||||||||||||||||||.|.|||:|||||||||||||||||||||||||.||||||||||||||
Mouse   586 LSYQVHREIPQAERYQEALPTVANSTGPHAASCFGAKKGKDEWFSRGKKPTEDPANDTVDFPKRT 650

Human   651 SPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAI 715
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   651 SPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAI 715

Human   716 ADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILN 780
            |:|||:||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||
Mouse   716 AELLTSEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVVSILN 780

Human   781 TINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWK 845
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   781 TINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWK 845

Human   846 KSDFQVNLNNASRSQSSHSYDDSTLPLIDRNQKSDKKPDREEIQMSNMGSNTKSLDNNYSTPNER 910
            |||||||||||||||||||||||||||||||||||||||||||.|||||||||||||||||.|||
Mouse   846 KSDFQVNLNNASRSQSSHSYDDSTLPLIDRNQKSDKKPDREEIPMSNMGSNTKSLDNNYSTLNER 910

Human   911 GDHNRTLDRSGDLGDMEPLKGTTPLMQDEGQESLEEELDVLVLDDEGGQVSYPSMQKI 968
            ||||||||||||||||||||| .||||||||||||||||||||||||.||||..||||
Mouse   911 GDHNRTLDRSGDLGDMEPLKG-APLMQDEGQESLEEELDVLVLDDEGNQVSYSPMQKI 967

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTNND1	NP_001078927.1	Necessary and sufficient for interaction with CCDC85B. /evidence=ECO:0000269|PubMed:25009281	1..357		347/355 (98%)
		Nuclear localization signal (NLS). /evidence=ECO:0000250|UniProtKB:P30999	299..306		6/6 (100%)
		ARM 1	358..395		35/36 (97%)
		armadillo repeat	368..393	CDD:293788	24/24 (100%)
		ARM	397..437	CDD:214547	38/39 (97%)
		ARM 2	398..437		37/38 (97%)
		armadillo repeat	401..437	CDD:293788	34/35 (97%)
		Arm	440..481	CDD:425727	40/40 (100%)
		ARM 3	441..475		33/33 (100%)
		armadillo repeat	444..479	CDD:293788	34/34 (100%)
		ARM 4	476..516		39/39 (100%)
		armadillo repeat	486..537	CDD:293788	50/50 (100%)
		Nuclear localization signal (NLS). /evidence=ECO:0000250|UniProtKB:P30999	521..528		6/6 (100%)
		ARM 5	534..573		38/38 (100%)
		Nuclear localization signal (NLS). /evidence=ECO:0000250|UniProtKB:P30999	568..575		6/6 (100%)
		ARM 6	583..624		37/40 (93%)
		Nuclear localization signal (NLS). /evidence=ECO:0000250|UniProtKB:P30999	622..629		6/6 (100%)
		ARM 7	653..693		39/39 (100%)
		armadillo repeat	656..693	CDD:293788	36/36 (100%)
		ARM 8	700..739		36/38 (95%)
		ARM	703..738	CDD:214547	32/34 (94%)
		armadillo repeat	703..737	CDD:293788	31/33 (94%)
		ARM 9	740..780		38/39 (97%)
		armadillo repeat	744..787	CDD:293788	41/42 (98%)
		ARM 10	781..826		44/44 (100%)
		armadillo repeat	793..829	CDD:293788	35/35 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	855..944		84/88 (95%)
Ctnnd1	XP_006498688.1	armadillo repeat	368..393	CDD:293788	24/24 (100%)
		ARM	397..437	CDD:214547	38/39 (97%)
		armadillo repeat	401..437	CDD:293788	34/35 (97%)
		Arm	440..481	CDD:425727	40/40 (100%)
		armadillo repeat	444..479	CDD:293788	34/34 (100%)
		armadillo repeat	486..537	CDD:293788	50/50 (100%)
		Syo1_like	632..>740	CDD:474028	104/107 (97%)
		armadillo repeat	656..693	CDD:293788	36/36 (100%)
		ARM	703..738	CDD:214547	32/34 (94%)
		armadillo repeat	703..737	CDD:293788	31/33 (94%)
		armadillo repeat	793..829	CDD:293788	35/35 (100%)