Sequence 1: | NP_000672.3 | Gene: | ADRA2A / 150 | HGNCID: | 281 | Length: | 465 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001262715.1 | Gene: | Octalpha2R / 42258 | FlyBaseID: | FBgn0038653 | Length: | 740 | Species: | Drosophila melanogaster |
Alignment Length: | 631 | Identity: | 190/631 - (30%) |
---|---|---|---|
Similarity: | 265/631 - (41%) | Gaps: | 198/631 - (31%) |
- Green bases have known domain annotations that are detailed below.
Human 9 AEGSFAPMGSL-QPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAG----LLMLLTVFGNVL 68
Human 69 VIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCT 133
Human 134 SSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQP 198
Human 199 AEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTR-------------------- 243
Human 244 -----VP-PSRRGPDA-----------VAAPPGGTE----------------------------- 262
Human 263 ------RRPNGLGPER----SAGPGGAEAEPLP-----------TQLNGAPGEPAPAGP------ 300
Human 301 --------RDTDALD---LEESSSSDHAERPPGPRRPERGPRGK-----GKARASQV-KPGDSLP 348
Human 349 RRGPGATGIG--------------------------------TPAAGPGEERVGAAKASRWRGRQ 381
Human 382 ---------------------------------NREKRFTFVLAVVIGVFVVCWFPFFFTYTLT- 412
Human 413 --AVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKIL 456 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
ADRA2A | NP_000672.3 | 7tmA_alpha2A_AR | 49..452 | CDD:320445 | 176/584 (30%) |
TM helix 1 | 51..75 | CDD:320445 | 11/27 (41%) | ||
TM helix 2 | 84..106 | CDD:320445 | 9/21 (43%) | ||
TM helix 3 | 122..144 | CDD:320445 | 12/21 (57%) | ||
TM helix 4 | 167..183 | CDD:320445 | 6/15 (40%) | ||
TM helix 5 | 209..232 | CDD:320445 | 10/22 (45%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 242..368 | 39/267 (15%) | |||
PHA03307 | 244..>389 | CDD:223039 | 44/294 (15%) | ||
TM helix 6 | 388..410 | CDD:320445 | 10/21 (48%) | ||
TM helix 7 | 420..445 | CDD:320445 | 14/24 (58%) | ||
Octalpha2R | NP_001262715.1 | 7tm_1 | 132..>315 | CDD:278431 | 92/186 (49%) |
7tm_4 | 133..>252 | CDD:304433 | 67/118 (57%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 1 | 1.000 | 273 | 1.000 | Domainoid score | I1790 |
eggNOG | 1 | 0.900 | - | - | E33208_3BC1G | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 1 | 1.000 | - | - | H47944 | |
Inparanoid | 1 | 1.050 | 310 | 1.000 | Inparanoid score | I2603 |
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D323202at33208 | |
OrthoFinder | 1 | 1.000 | - | - | FOG0001303 | |
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 1 | 1.100 | - | - | O | PTHR24248 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3253 |
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
9 | 9.000 |