| Sequence 1: | NP_000672.3 | Gene: | ADRA2A / 150 | HGNCID: | 281 | Length: | 465 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_997520.3 | Gene: | adra2a / 266750 | ZFINID: | ZDB-GENE-021010-1 | Length: | 388 | Species: | Danio rerio |
| Alignment Length: | 440 | Identity: | 268/440 - (60%) |
|---|---|---|---|
| Similarity: | 308/440 - (70%) | Gaps: | 59/440 - (13%) |
- Green bases have known domain annotations that are detailed below.
|
Human 30 GTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASAD 94
Human 95 ILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLK 159
Human 160 RTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPC 224
Human 225 LIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLN 289
Human 290 GAPGEPAPAGPRDTD---ALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRG 351
Human 352 PGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTA-VG 415
Human 416 CSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV 465 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ADRA2A | NP_000672.3 | 7tmA_alpha2A_AR | 49..452 | CDD:320445 | 252/406 (62%) |
| TM helix 1 | 51..75 | CDD:320445 | 16/23 (70%) | ||
| TM helix 2 | 84..106 | CDD:320445 | 20/21 (95%) | ||
| TM helix 3 | 122..144 | CDD:320445 | 19/21 (90%) | ||
| TM helix 4 | 167..183 | CDD:320445 | 9/15 (60%) | ||
| TM helix 5 | 209..232 | CDD:320445 | 17/22 (77%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 242..368 | 38/128 (30%) | |||
| PHA03307 | 244..>389 | CDD:223039 | 51/147 (35%) | ||
| TM helix 6 | 388..410 | CDD:320445 | 20/21 (95%) | ||
| TM helix 7 | 420..445 | CDD:320445 | 22/24 (92%) | ||
| adra2a | NP_997520.3 | 7tm_4 | 31..>165 | CDD:304433 | 111/133 (83%) |
| 7tm_1 | 39..364 | CDD:278431 | 234/379 (62%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 208..291 | 39/129 (30%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 432 | 1.000 | Domainoid score | I3919 |
| eggNOG | 1 | 0.900 | - | - | E33208_3BC1G | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H47944 | |
| Inparanoid | 1 | 1.050 | 493 | 1.000 | Inparanoid score | I6579 |
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG43153 | |
| OrthoDB | 1 | 1.010 | - | - | D217516at7742 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001303 | |
| OrthoInspector | 1 | 1.000 | - | - | oto42325 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_113344 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24248 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3253 |
| SonicParanoid | 1 | 1.000 | - | - | X801 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| ZFIN | 1 | 1.500 | - | - | ||
| 17 | 17.370 | |||||