| Sequence 1: | NP_001895.1 | Gene: | CTNNB1 / 1499 | HGNCID: | 2514 | Length: | 781 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_445809.3 | Gene: | Ctnnb1 / 84353 | RGDID: | 70487 | Length: | 781 | Species: | Rattus norvegicus |
| Alignment Length: | 781 | Identity: | 780/781 - (99%) |
|---|---|---|---|
| Similarity: | 780/781 - (99%) | Gaps: | 0/781 - (0%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYE 65
Human 66 WEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQ 130
Human 131 MLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMV 195
Human 196 SAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLH 260
Human 261 NLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALV 325
Human 326 NIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSD 390
Human 391 AATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAG 455
Human 456 DREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALC 520
Human 521 PANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVH 585
Human 586 NRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEG 650
Human 651 VATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPS 715
Human 716 YRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD 780
Human 781 L 781 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CTNNB1 | NP_001895.1 | Interaction with VCL. /evidence=ECO:0000250 | 2..23 | 20/20 (100%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 34..57 | 22/22 (100%) | |||
| CTNNAbd_CTNNB1 | 78..151 | CDD:439241 | 72/72 (100%) | ||
| SRP1 | 142..>431 | CDD:227396 | 288/288 (100%) | ||
| ARM 1 | 151..191 | 39/39 (100%) | |||
| armadillo repeat | 153..178 | CDD:293788 | 24/24 (100%) | ||
| Interaction with BCL9. /evidence=ECO:0000269|PubMed:17052462 | 156..178 | 21/21 (100%) | |||
| armadillo repeat | 188..221 | CDD:293788 | 32/32 (100%) | ||
| ARM 2 | 193..234 | 40/40 (100%) | |||
| armadillo repeat | 230..262 | CDD:293788 | 31/31 (100%) | ||
| ARM | 230..262 | CDD:214547 | 31/31 (100%) | ||
| ARM 3 | 235..276 | 40/40 (100%) | |||
| armadillo repeat | 270..306 | CDD:293788 | 35/35 (100%) | ||
| ARM 4 | 277..318 | 40/40 (100%) | |||
| armadillo repeat | 312..347 | CDD:293788 | 34/34 (100%) | ||
| ARM 5 | 319..360 | 40/40 (100%) | |||
| ARM | 350..390 | CDD:214547 | 39/39 (100%) | ||
| armadillo repeat | 354..389 | CDD:293788 | 34/34 (100%) | ||
| ARM 6 | 361..389 | 27/27 (100%) | |||
| ARM 7 | 400..441 | 40/40 (100%) | |||
| armadillo repeat | 402..427 | CDD:293788 | 24/24 (100%) | ||
| Arm | 431..473 | CDD:425727 | 41/41 (100%) | ||
| armadillo repeat | 435..473 | CDD:293788 | 37/37 (100%) | ||
| ARM 8 | 442..484 | 41/41 (100%) | |||
| armadillo repeat | 482..517 | CDD:293788 | 34/34 (100%) | ||
| ARM 9 | 489..530 | 40/40 (100%) | |||
| armadillo repeat | 524..582 | CDD:293788 | 57/57 (100%) | ||
| ARM 10 | 531..571 | 39/39 (100%) | |||
| Arm | 583..622 | CDD:425727 | 38/38 (100%) | ||
| armadillo repeat | 587..621 | CDD:293788 | 33/33 (100%) | ||
| ARM 11 | 594..636 | 41/41 (100%) | |||
| armadillo repeat | 629..662 | CDD:293788 | 32/32 (100%) | ||
| ARM 12 | 637..666 | 28/28 (100%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 705..781 | 74/75 (99%) | |||
| Interaction with SCRIB. /evidence=ECO:0000250 | 772..781 | 8/8 (100%) | |||
| Ctnnb1 | NP_445809.3 | Interaction with VCL. /evidence=ECO:0000250 | 2..23 | 20/20 (100%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 34..57 | 22/22 (100%) | |||
| CTNNAbd_CTNNB1 | 78..151 | CDD:439241 | 72/72 (100%) | ||
| SRP1 | 142..>431 | CDD:227396 | 288/288 (100%) | ||
| ARM 1 | 151..191 | 39/39 (100%) | |||
| armadillo repeat | 153..178 | CDD:293788 | 24/24 (100%) | ||
| Interaction with BCL9. /evidence=ECO:0000250 | 156..178 | 21/21 (100%) | |||
| armadillo repeat | 188..221 | CDD:293788 | 32/32 (100%) | ||
| ARM 2 | 193..234 | 40/40 (100%) | |||
| armadillo repeat | 230..262 | CDD:293788 | 31/31 (100%) | ||
| ARM | 230..262 | CDD:214547 | 31/31 (100%) | ||
| ARM 3 | 235..276 | 40/40 (100%) | |||
| armadillo repeat | 270..306 | CDD:293788 | 35/35 (100%) | ||
| ARM 4 | 277..318 | 40/40 (100%) | |||
| armadillo repeat | 312..347 | CDD:293788 | 34/34 (100%) | ||
| ARM 5 | 319..360 | 40/40 (100%) | |||
| ARM | 350..390 | CDD:214547 | 39/39 (100%) | ||
| armadillo repeat | 354..389 | CDD:293788 | 34/34 (100%) | ||
| ARM 6 | 361..389 | 27/27 (100%) | |||
| ARM 7 | 400..441 | 40/40 (100%) | |||
| armadillo repeat | 402..427 | CDD:293788 | 24/24 (100%) | ||
| Arm | 431..473 | CDD:425727 | 41/41 (100%) | ||
| armadillo repeat | 435..473 | CDD:293788 | 37/37 (100%) | ||
| ARM 8 | 442..484 | 41/41 (100%) | |||
| armadillo repeat | 482..517 | CDD:293788 | 34/34 (100%) | ||
| ARM 9 | 489..530 | 40/40 (100%) | |||
| armadillo repeat | 524..582 | CDD:293788 | 57/57 (100%) | ||
| ARM 10 | 531..571 | 39/39 (100%) | |||
| Arm | 583..622 | CDD:425727 | 38/38 (100%) | ||
| armadillo repeat | 587..621 | CDD:293788 | 33/33 (100%) | ||
| ARM 11 | 594..636 | 41/41 (100%) | |||
| armadillo repeat | 629..662 | CDD:293788 | 32/32 (100%) | ||
| ARM 12 | 637..666 | 28/28 (100%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 720..781 | 60/60 (100%) | |||
| Interaction with SCRIB. /evidence=ECO:0000250 | 772..781 | 8/8 (100%) |