DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Slc39a7 and Zip71B

DIOPT Version :9

Sequence 1:	NP_001071177.1	Gene:	Slc39a7 / 14977	MGIID:	95909	Length:	476	Species:	Mus musculus
Sequence 2:	NP_001097608.1	Gene:	Zip71B / 39626	FlyBaseID:	FBgn0036461	Length:	572	Species:	Drosophila melanogaster

Alignment Length:	349	Identity:	110/349 - (31%)
Similarity:	174/349 - (49%)	Gaps:	53/349 - (15%)

- Green bases have known domain annotations that are detailed below.

Mouse   143 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALEPHSHH 207
            |.||....:::||.....:.|:|: ..|..::.:|:.|:|.|.|.|.|||.:||:||||.....|
  Fly   243 WIYASITMLILSACGLLGILLVPL-MKSAAYQEILKFLVSIAVGTLAGDALMHLLPHALFKEEKH 306

Mouse   208 APEQPG-----HGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKG---GHGHSHGHGDRHAH 264
            ..|..|     ..|.||.:..:| .|...|:.:..:: :|..:..:||   |||||||||  |:|
  Fly   307 EEEVTGINPLESDHKHSNEAALL-CGCTFLAALFMYM-LENLIPLLKGGKPGHGHSHGHG--HSH 367

Mouse   265 GDSHTHGDRHECSSKEKPSTEEEKEVGGLRKRRGGNTGPRDGPVKPQSP--EEEKAGSDLRVSGY 327
            |.||.|        .|||:.::..::          ..||:..|..|..  :|:.....|....:
  Fly   368 GRSHGH--------MEKPAAKDAIDL----------PPPRELNVMLQEAKLDEKTPDRPLTPVAF 414

Mouse   328 LNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQL 392
            :.:..|..||.||||||||:|......|..|...||.||:|||:||||:|:|:|.|.::|:.:.:
  Fly   415 MVIIGDGLHNLTDGLAIGAAFASDPVTGFATAFAVLCHELPHELGDFALLLQTGVSMRRAVYMNI 479

Mouse   393 VTAIGALAGTACALLTEGGAVDSDVAGGAGPG---WVLPFTAGGFIYVATVSVLPELL------R 448
            |:::.:..|.:..|.          ..|.|.|   |:...|||.|:|:|...::|.:.      :
  Fly   480 VSSVLSFVGMSVGLF----------IAGIGDGMTQWIYAATAGSFLYIAFADLVPTMSVAHNPEK 534

Mouse   449 EASPLQSLLEVLG-LLGGVAMMVL 471
            ...|...::::.| ||||:.|:.:
  Fly   535 AKDPKGIIIQIFGILLGGLIMLAI 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Slc39a7	NP_001071177.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	35..131
		Zip	140..453	CDD:280666	103/328 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	249..320		25/75 (33%)
Zip71B	NP_001097608.1	Zip	242..559	CDD:280666	110/349 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0428
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D657777at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820