Protein Alignment CTNS and Ctns

DIOPT Version :10

• Sequence 1: NP_001026851.2
• Gene: CTNS / 1497
• HGNCID: 2518
• Length: 400
• Species: Homo sapiens
• Sequence 2: NP_651116.1
• Gene: Ctns / 42723
• FlyBaseID: FBgn0039045
• Length: 397
• Species: Drosophila melanogaster
• Alignment Length: 379
• Identity: 162/379 - (42%)
• Similarity: 223/379 - (58%)
• Gaps: 52/379 - (13%)

Human    39 STNVSLTLRPPLNATLVI----TFEITFRSKNITIL-------------------EL-------- 72
            ||:...||...|.||:.:    :.::|..|.:||:|                   |:
  Fly     4 STHRLTTLLLLLLATVALGNAQSSQLTVDSHDITVLLNSNETFLVFANGLLDSDVEVALGTDSED 68

Human    73 -----PDEVVVPPGVT-NSSFQVTSQNVGQLTVYLHGNHSNQTGPR---IRFLVIRSSAISIINQ 128
                 |...|.|.|.| |.|..:|....|.:.|....:.:|:...:   :|..|.:|.|:...:.
  Fly    69 HLLLDPATFVYPAGSTRNQSVVITGLKAGNVKVVADSDDANKEIVKDVFVRVTVAKSRALIYTSI 133

Human   129 VIGWIYFVAWSISFYPQVIMNWRRKSVIGLSFDFVALNLTGFVAYSVFNIGLLWVPYIKEQFLLK 193
            :.||:||||||:|||||:..|:|||||.||:|||:|||:.||..||:||.||.::..::.::.::
  Fly   134 IFGWVYFVAWSVSFYPQIWSNYRRKSVEGLNFDFLALNIVGFTLYSMFNCGLYFIEDLQNEYEVR 198

Human   194 YPNGVNPVNSNDVFFSLHAVVLTLIIIVQCCLYERGGQRVSWPAIGFLVLAWLFAFVTMIVAAV- 257
            ||.|||||..|||.|||||:..|.|.|:||..|:|..||||:.|.|.|.   :||.|.::.|.:
  Fly   199 YPLGVNPVMLNDVVFSLHAMFATCITILQCFFYQRAQQRVSFIAYGILA---IFAVVVVVSAGLA 260

Human   258 --GVTTWLQFLFCFSYIKLAVTLVKYFPQAYMNFYYKSTEGWSIGNVLLDFTGGSFSLLQMFLQS 320
              .|..||.||:..||:||.:|::||.|||.||:..|||.||||||:|||||||:.|:|||.|.:
  Fly   261 GGSVIHWLDFLYYCSYVKLTITIIKYVPQALMNYRRKSTSGWSIGNILLDFTGGTLSMLQMILNA 325

Human   321 YNNDQWTLIFGDPTKFGLGVFSIVFDVVFFIQHFCLYRKRPGLQAARTGSGSRL 374
            :|.|.|..|||||||||||:||::|||.|.:||:..||.      :|..|.|.|
  Fly   326 HNYDDWVSIFGDPTKFGLGLFSVLFDVFFMLQHYVFYRH------SRESSSSDL 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTNS	NP_001026851.2	2A43	125..357	CDD:130026	128/234 (55%)
Ctns	NP_651116.1	2A43	129..362	CDD:130026	128/235 (54%)