DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gsx1 and Antp

DIOPT Version :9

Sequence 1:	NP_032204.1	Gene:	Gsx1 / 14842	MGIID:	95842	Length:	261	Species:	Mus musculus
Sequence 2:	NP_996167.1	Gene:	Antp / 40835	FlyBaseID:	FBgn0260642	Length:	378	Species:	Drosophila melanogaster

Alignment Length:	234	Identity:	72/234 - (30%)
Similarity:	89/234 - (38%)	Gaps:	77/234 - (32%)

- Green bases have known domain annotations that are detailed below.

Mouse    21 PEGSPPPL--------------FPYAVPPPHALHGLSPGACHARKAGLLCVCPLCVTASQLHGPP 71
            |||..|||              .|:.:..|.|..|.:       ..|:    |......|.|...
  Fly   175 PEGGSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYT-------DVGV----PDVTEVHQNHHNM 228

Mouse    72 G--------PPALPLLKASFPPFGSQYCHAPLGRQHSVSPGVAHGPAAAAAAAALYQTSYPLPDP 128
            |        ||      ...||.|..:......:.|...|| .|.|              |..:|
  Fly   229 GMYQQQSGVPP------VGAPPQGMMHQGQGPPQMHQGHPG-QHTP--------------PSQNP 272

Mouse   129 RQFHCISVDSSSNQLPS---------------SKRMRTAFTSTQLLELEREFASNMYLSRLRRIE 178
                    :|.|:.:||               .||.|..:|..|.||||:||..|.||:|.||||
  Fly   273 --------NSQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIE 329

Mouse   179 IATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGAGAG 217
            ||..|.|:|:|:||||||||:|.|||.|.....|..|.|
  Fly   330 IAHALCLTERQIKIWFQNRRMKWKKENKTKGEPGSGGEG 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gsx1	NP_032204.1	SNAG domain. /evidence=ECO:0000250	1..20
		Homeobox	150..203	CDD:395001	32/52 (62%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	201..261		7/17 (41%)
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	34/170 (20%)
Antp	NP_996167.1	Homeobox	301..354	CDD:395001	32/52 (62%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810