DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SAMD11 and gmeb-3

DIOPT Version :9

Sequence 1:	NP_001372569.1	Gene:	SAMD11 / 148398	HGNCID:	28706	Length:	845	Species:	Homo sapiens
Sequence 2:	NP_497762.2	Gene:	gmeb-3 / 175487	WormBaseID:	WBGene00008092	Length:	376	Species:	Caenorhabditis elegans

Alignment Length:	196	Identity:	47/196 - (23%)
Similarity:	77/196 - (39%)	Gaps:	40/196 - (20%)

- Green bases have known domain annotations that are detailed below.

Human    72 AYLSLHEAAPHLHLPRDPLALERFSATAAAAPDFQPLLDNGEPCIEVECGANRALLYVRKL-CQG 135
            :|..|...:.|:..|..||     :||.                :.|.||..:.:::::.. |.|
Worm    53 SYTYLDTPSEHIWTPIVPL-----NATT----------------VPVTCGYVKGIMHLKLFRCPG 96

Human   136 SKGPSIRHRGEWLTPNEFQFVSGRETAKDWKRSIRHKGKSLKTLMSKGILQV--HPPIC--DCPG 196
            .:...|.:..::|||.:|..:.|:...||||..||.:..||:||:....:..  |..||  .|..
Worm    97 IRQACIEYESQYLTPKQFTELGGKGRQKDWKACIRVENVSLRTLLENKTIDFYNHKSICHGQCQS 161

Human   197 CRI-----SSPVNRGRLADKRTVALPAARNLKKERTPSFSASDGDSD----GSGPTCGRRPGLKQ 252
            ...     .:|||:..|.|     :.|:.:...|.|...|....:..    |.|...|::...|.
Worm   162 RNYMNSTGRAPVNKRHLED-----VLASGDDASEPTEQSSGQISEEPIKKRGRGRPAGKKNKAKL 221

Human   253 E 253
            |
Worm   222 E 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SAMD11	NP_001372569.1	SAND	113..185	CDD:396076	21/72 (29%)
SAMD11	NP_001372569.1	SAM_Samd7,11	704..771	CDD:188978
gmeb-3	NP_497762.2	SAND	74..147	CDD:128554	22/88 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4333
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900