DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SAMD11 and lin-61

DIOPT Version :9

Sequence 1:	NP_001372569.1	Gene:	SAMD11 / 148398	HGNCID:	28706	Length:	845	Species:	Homo sapiens
Sequence 2:	NP_001122501.1	Gene:	lin-61 / 172467	WormBaseID:	WBGene00003041	Length:	612	Species:	Caenorhabditis elegans

Alignment Length:	126	Identity:	27/126 - (21%)
Similarity:	38/126 - (30%)	Gaps:	46/126 - (36%)

- Green bases have known domain annotations that are detailed below.

Human   461 PLLSPQNAPHVAL----------------GP---------HLRPPFLGVPSALCQTPGYGFLPPA 500
            ||....|..|||.                ||         |:...|: .|....:......:||.
Worm   439 PLAQQFNNLHVASILKFCKTEGYLIVGMDGPDALEDSFPIHINNTFM-FPVGYAEKYNLELVPPD 502

Human   501 QAE-MFAWQQELLRKQNLARLELPADL----------------LRQKELESARPQLLAPET 544
            :.: .|.| .|.|.|::..  .||.||                ||.:..:....|.:.|.|
Worm   503 EFKGTFRW-DEYLEKESAE--TLPLDLFKPMPSQERLDKFKVGLRLEAADMCENQFICPAT 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SAMD11	NP_001372569.1	SAND	113..185	CDD:396076
SAMD11	NP_001372569.1	SAM_Samd7,11	704..771	CDD:188978
lin-61	NP_001122501.1	MBT	146..248	CDD:214723
		MBT	283..383	CDD:214723
		MBT	433..505	CDD:280910	13/66 (20%)
		MBT	511..607	CDD:214723	12/52 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C161457488
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930