Protein Alignment DIRAS1 and RHB1

DIOPT Version :10

• Sequence 1: XP_047294230.1
• Gene: DIRAS1 / 148252
• HGNCID: 19127
• Length: 232
• Species: Homo sapiens
• Sequence 2: NP_009956.2
• Gene: RHB1 / 850392
• SGDID: S000000622
• Length: 209
• Species: Saccharomyces cerevisiae
• Alignment Length: 205
• Identity: 63/205 - (30%)
• Similarity: 108/205 - (52%)
• Gaps: 28/205 - (13%)

Human    43 RVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQR 107
            ::.:.||..|||::|.:|||:..|.::|.||||:.:.::|......|||:|.||.|..:...:..
Yeast    18 KIALIGARNVGKTTLTVRFVESRFVESYYPTIENEFTRIIPYKSHDCTLEILDTAGQDEVSLLNI 82

Human   108 LSISKGHAFILVFSVTSKQSLEELGPIY--KLIVQIKGSVEDIPVMLVGNKCD------ETQREV 164
            .|::.....||.:|:.::.|. :|.||.  ||:.|:  ..:::||:|||.|.|      ..:|.|
Yeast    83 KSLTGVRGIILCYSIINRASF-DLIPILWDKLVDQL--GKDNLPVILVGTKADLGRSTKGVKRCV 144

Human   165 DTREAQAVA-------QEWKCAFMETSAKMNYNVKELFQELLTLETRRNMSLNIDGKRSGKQKRT 222
            ...|.:.:|       :..:.||:|.||:::|||:|.|..||....|...:|.:|.:.:
Yeast   145 TKAEGEKLASTIGSQDKRNQAAFIECSAELDYNVEETFMLLLKQMERVEGTLGLDAENN------ 203

Human   223 DRVKGKCTLM 232
                .||::|
Yeast   204 ----NKCSIM 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIRAS1	XP_047294230.1	P-loop containing Nucleoside Triphosphate Hydrolases	41..202	CDD:476819	57/173 (33%)
RHB1	NP_009956.2	RheB	16..209	CDD:206709	62/203 (31%)