Protein Alignment DIRAS1 and CG8519

DIOPT Version :10

• Sequence 1: XP_047294230.1
• Gene: DIRAS1 / 148252
• HGNCID: 19127
• Length: 232
• Species: Homo sapiens
• Sequence 2: NP_648054.2
• Gene: CG8519 / 38745
• FlyBaseID: FBgn0035711
• Length: 207
• Species: Drosophila melanogaster
• Alignment Length: 192
• Identity: 54/192 - (28%)
• Similarity: 90/192 - (46%)
• Gaps: 21/192 - (10%)

Human    41 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDT--TGSHQFP 103
            :.::.|.||..||||:|::||:...:...|....|:.|:.....|......:|.||  ....::|
  Fly    15 ELKIAVIGAPSVGKSALIVRFLTKRYIGEYDHQTENRYKHEAMVDGEPVLFEILDTCPKAEDEYP 79

Human   104 AMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVE-DIPVMLVGNKCDETQ-REVDT 166
            ....| :......:||:|:|.::|       :..|.:.|..:: |.||.|..||.|... |:|..
  Fly    80 NAAEL-VQWADGLLLVYSITDRKS-------FNYIRRAKSDLQSDTPVQLCANKVDMVHLRQVSR 136

Human   167 REAQAVAQEWKCAFMETSAKMNYN-VKELFQELLTLETRRNMSLNIDGKRSGKQKRTDRVKG 227
            .|.:.:|::::|.|.|.||..:.: |.|:|.||.. |.       :..||..||...:|:.|
  Fly   137 DEGEILAKDFECKFSEVSAADHVDQVAEVFNELCK-EV-------LASKRKSKQSLLERMLG 190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIRAS1	XP_047294230.1	P-loop containing Nucleoside Triphosphate Hydrolases	41..202	CDD:476819	47/165 (28%)
CG8519	NP_648054.2	P-loop containing Nucleoside Triphosphate Hydrolases	17..173	CDD:476819	47/164 (29%)