Protein Alignment DIRAS1 and Ras64B

DIOPT Version :10

• Sequence 1: XP_047294230.1
• Gene: DIRAS1 / 148252
• HGNCID: 19127
• Length: 232
• Species: Homo sapiens
• Sequence 2: NP_523917.2
• Gene: Ras64B / 38494
• FlyBaseID: FBgn0003206
• Length: 192
• Species: Drosophila melanogaster
• Alignment Length: 200
• Identity: 67/200 - (33%)
• Similarity: 112/200 - (56%)
• Gaps: 14/200 - (7%)

Human    38 QSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQF 102
            |...|::||.|.||||||::.::|::..|...|.|||||:|.:..:.|.....|.|.||.|..:|
  Fly     2 QMQTYKLVVVGGGGVGKSAITIQFIQSYFVTDYDPTIEDSYTKQCNIDDVPAKLDILDTAGQEEF 66

Human   103 PAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVGNKCD-ETQREVDT 166
            .||:...:..|..|:|||::....|.:|:....:.|:::|.. ::.|:::|||||| :.|::|..
  Fly    67 SAMREQYMRSGEGFLLVFALNDHSSFDEIPKFQRQILRVKDR-DEFPMLMVGNKCDLKHQQQVSL 130

Human   167 REAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLETRRNMS----LNIDGKRSGKQKRTDRVKG 227
            .|||..::.....::|.|||:..||.:.|.||:.:..:..::    :..|.|:.||:
  Fly   131 EEAQNTSRNLMIPYIECSAKLRVNVDQAFHELVRIVRKFQIAERPFIEQDYKKKGKR-------- 187

Human   228 KCTLM 232
            ||.||
  Fly   188 KCCLM 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIRAS1	XP_047294230.1	P-loop containing Nucleoside Triphosphate Hydrolases	41..202	CDD:476819	58/161 (36%)
Ras64B	NP_523917.2	M_R_Ras_like	4..167	CDD:133345	58/163 (36%)