Protein Alignment DIRAS1 and Rap1

DIOPT Version :10

• Sequence 1: XP_047294230.1
• Gene: DIRAS1 / 148252
• HGNCID: 19127
• Length: 232
• Species: Homo sapiens
• Sequence 2: NP_476857.1
• Gene: Rap1 / 38244
• FlyBaseID: FBgn0004636
• Length: 184
• Species: Drosophila melanogaster
• Alignment Length: 193
• Identity: 76/193 - (39%)
• Similarity: 123/193 - (63%)
• Gaps: 12/193 - (6%)

Human    41 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAM 105
            :|::||.|:||||||:|.::||:..|.:.|.|||||:||:.:..|...|.|:|.||.|:.||.||
  Fly     3 EYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAM 67

Human   106 QRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVGNKCD-ETQREVDTREA 169
            :.|.:..|..|:||:|:|::.:..:|..:.:.|:::| ..:|:|::||||||| |.:|.|.....
  Fly    68 RDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVK-DTDDVPMVLVGNKCDLEEERVVGKELG 131

Human   170 QAVAQEWKCAFMETSAKMNYNVKELFQELLTLETRRNMSLNIDGKRSGKQKRTDRVKGKCTLM 232
            :.:|.::.|||||||||...||.::|.:|:       ..:|   |:|.::|:....|..|.|:
  Fly   132 KNLATQFNCAFMETSAKAKVNVNDIFYDLV-------RQIN---KKSPEKKQKKPKKSLCVLL 184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIRAS1	XP_047294230.1	P-loop containing Nucleoside Triphosphate Hydrolases	41..202	CDD:476819	69/161 (43%)
Rap1	NP_476857.1	Rap1	3..165	CDD:133375	69/169 (41%)