Protein Alignment DIRAS1 and Rgk2

DIOPT Version :10

• Sequence 1: XP_047294230.1
• Gene: DIRAS1 / 148252
• HGNCID: 19127
• Length: 232
• Species: Homo sapiens
• Sequence 2: NP_001286577.1
• Gene: Rgk2 / 37132
• FlyBaseID: FBgn0085419
• Length: 742
• Species: Drosophila melanogaster
• Alignment Length: 252
• Identity: 66/252 - (26%)
• Similarity: 113/252 - (44%)
• Gaps: 49/252 - (19%)

Human     9 ARQARSGVLAAGTSPPGPGRPPAAGK--------------MPEQSND--------YRVVVFGAGG 51
            :|::||......|:.....|.|..|.              .|:.|.:        ||||:.|..|
  Fly   472 SRRSRSNTSVNSTNSRASERSPFEGSCCGAGYANVDSLPATPDDSENLDPPPPARYRVVMLGDAG 536

Human    52 VGKSSLVLRFVKGTFRDTYIPT--IEDTYRQVISCDKSVCTLQITDTTGSHQF---PAMQ----- 106
            |||::||.:|:...:..||..:  ::|.:.     :|:|..| :.|......|   |:::
  Fly   537 VGKTALVNQFMTSEYMHTYDASLVLDDEFG-----EKTVSVL-LDDEESDMVFIDHPSVEMSVEN 595

Human   107 RLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVGNKCDETQ-REVDTREAQ 170
            .||..:.|..::||||..:.|......|...:.| :...:|..|:|||||.|..: |.:.::|.:
  Fly   596 SLSTYEPHGCVVVFSVVDRSSFRVAEEIINYLWQ-ENYTKDKAVILVGNKADLARARLITSQEGK 659

Human   171 AVAQEWKCAFMETSAKMNYNVKELFQELL---TLETRRNMSLNIDGKRSGKQKRTDR 224
            |:|......|:|||:.:.:||.||...:|   .|:.:|      :.|.:..:.:|.|
  Fly   660 ALAASRDAKFIETSSGIQHNVDELLVGILKQMRLKEKR------EKKATASKMKTSR 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIRAS1	XP_047294230.1	P-loop containing Nucleoside Triphosphate Hydrolases	41..202	CDD:476819	52/182 (29%)
Rgk2	NP_001286577.1	RGK	527..742	CDD:206715	57/197 (29%)