Protein Alignment DIRAS1 and Ric

DIOPT Version :10

• Sequence 1: XP_047294230.1
• Gene: DIRAS1 / 148252
• HGNCID: 19127
• Length: 232
• Species: Homo sapiens
• Sequence 2: NP_477211.1
• Gene: Ric / 36776
• FlyBaseID: FBgn0265605
• Length: 264
• Species: Drosophila melanogaster
• Alignment Length: 241
• Identity: 85/241 - (35%)
• Similarity: 128/241 - (53%)
• Gaps: 26/241 - (10%)

Human     8 RARQARSGVLAAGTSP---PGPGR-------PPAAGKMPEQS-----NDYRVVVFGAGGVGKSSL 57
            |:.:.||...||.|..   |...|       ||   .:|.|:     ..|::|:.|.||||||::
  Fly    14 RSSKLRSCTSAADTDSMRVPSDHRDNGSLIKPP---PVPPQNMRGGLRVYKIVILGDGGVGKSAV 75

Human    58 VLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVFSV 122
            .|:||..:|.|.:.|||||:|:|....|.....|.|.||.|..:|.||:...:..|..||:.:||
  Fly    76 TLQFVSHSFLDYHDPTIEDSYQQQAVIDNEAALLDILDTAGQVEFTAMRDQYMRCGEGFIICYSV 140

Human   123 TSKQSLEELGPIYKLIVQIKGSVEDIPVMLVGNKCD-ETQREVDTREAQAVAQEWKCAFMETSAK 186
            |.:.|.:|.....|||.:::.| ||||::|:.||.| |:||.|.|.|.:.:|.::.|.|.||||.
  Fly   141 TDRHSFQEASEYRKLITRVRLS-EDIPLVLIANKVDLESQRRVTTEEGRNLANQFGCPFFETSAA 204

Human   187 MNYNVKELFQELLTLETRRNM--SLNIDGK----RSGKQKRTDRVK 226
            :.:.:.|.|..|:....|:.|  :|..|..    .:|::.|..|::
  Fly   205 LRHYIDEAFYTLVREIRRKEMHKALGTDSNSEKIHTGRRSRWWRIR 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIRAS1	XP_047294230.1	P-loop containing Nucleoside Triphosphate Hydrolases	41..202	CDD:476819	66/161 (41%)
Ric	NP_477211.1	Rit_Rin_Ric	58..229	CDD:206712	68/171 (40%)