Protein Alignment DIRAS1 and Rheb

DIOPT Version :10

• Sequence 1: XP_047294230.1
• Gene: DIRAS1 / 148252
• HGNCID: 19127
• Length: 232
• Species: Homo sapiens
• Sequence 2: NP_730950.2
• Gene: Rheb / 117332
• FlyBaseID: FBgn0041191
• Length: 182
• Species: Drosophila melanogaster
• Alignment Length: 176
• Identity: 64/176 - (36%)
• Similarity: 105/176 - (59%)
• Gaps: 10/176 - (5%)

Human    35 MPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGS 99
            ||  :.:..:.:.|...||||||.::||:|.|.|:|.||||:|:.::.........:::.||.|.
  Fly     1 MP--TKERHIAMMGYRSVGKSSLCIQFVEGQFVDSYDPTIENTFTKIERVKSQDYIVKLIDTAGQ 63

Human   100 HQ---FPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVGNKCD-ET 160
            .:   ||....:..   |.::||:|:||::|.|.:..||:.::.:.|. :.:||:|||||.| ..
  Fly    64 DEYSIFPVQYSMDY---HGYVLVYSITSQKSFEVVKIIYEKLLDVMGK-KYVPVVLVGNKIDLHQ 124

Human   161 QREVDTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLETRRN 206
            :|.|.|.|.:.:|:.|:.||:|||||.|.:|.::|.:||.|....|
  Fly   125 ERTVSTEEGKKLAESWRAAFLETSAKQNESVGDIFHQLLILIENEN 170

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIRAS1	XP_047294230.1	P-loop containing Nucleoside Triphosphate Hydrolases	41..202	CDD:476819	60/164 (37%)
Rheb	NP_730950.2	RheB	5..182	CDD:206709	62/170 (36%)