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Protein Alignment Gria1 and GluRIB

DIOPT Version :9

Sequence 1:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus
Sequence 2:	NP_001261621.2	Gene:	GluRIB / 44484	FlyBaseID:	FBgn0264000	Length:	1182	Species:	Drosophila melanogaster

Alignment Length:	1029	Identity:	413/1029 - (40%)
Similarity:	563/1029 - (54%)	Gaps:	167/1029 - (16%)

- Green bases have known domain annotations that are detailed below.

Mouse    14 GAVVGA----NFPNNIQIGGLFPNQQSQEHAAFRFA-----LSQLTEPPKLLPQIDIVNISDSFE 69
            |:.||.    :....|.:|.:|.....:..:||::|     |:..:...:|...:|::|.:|:|:
  Fly    27 GSGVGVSAQPSLTEKIPLGAIFEQGTDEVQSAFKYAMLNHNLNVSSRRFELQAYVDVINTADAFK 91

Mouse    70 MTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFP--VDTSN----QFVLQLRPE 128
            ::...|:|||:|||::.|.....:.:.|.|:.....:.|:||.||  |.|.:    .|.|.:||:
  Fly    92 LSRLICNQFSRGVYSMLGAVSPDSFDTLHSYSNTFQMPFVTPWFPEKVLTPSSGFLDFALSMRPD 156

Mouse   129 LQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLD--TAAEKNWQVTAVNILTTTEEGYRML--F 189
            ..:|:|..|..|.|:..:|:||:..||..||::..  ....:::||..|..::........|  .
  Fly   157 YHQAIIDTIQFYGWRKIIYLYDSHDGLLRLQQIYQGLRPGNESFQVELVKRISNVSMAIEFLHTL 221

Mouse   190 QDLEKKKERLVVVDCESERLNAILGQIVK-LEKNGIGYHYILANLGFMDIDLNKFKESGA-NVTG 252
            :.:.:.:.:.:|:||.:|....||.|.|: |......|||:|:.|...|...::..|.|| |:||
  Fly   222 EQIGRFENKHIVLDCPTEMAKQILIQHVRDLRLGRRTYHYLLSGLVMDDRWESEIIEFGAINITG 286

Mouse   253 FQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRID---- 313
            |::|:....:.......|:..|.:.......:.....:||.||.|.|:.|||..:.|::.|
  Fly   287 FRIVDTNRRLVREFYDSWKRLDPQMSVGAGRESISAQAALMYDAVFVLVEAFNKILRKKPDQFRN 351

Mouse   314 -ISRR---------------------------GNAG---------------------DCLANPAV 329
             :.||                           ||.|                     ||  |.|.
  Fly   352 NVQRRSQTLMVAQAAASTSSDGYNYSASGGGGGNGGAGGGFAGSDSGGSGGMASRALDC--NTAK 414

Mouse   330 ----PWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMK-HDGIRKIGYWNEDDKFV 389
                .|..|..|.|.|::|..|||||:::||:.|||.||||||:||. :..:.|:..||:|....
  Fly   415 GWVNAWEHGDKISRYLRKVEIEGLTGDIKFNDDGRRVNYTLHVVEMTVNSAMVKVAEWNDDAGLQ 479

Mouse   390 PA-ATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNA--NQFEGNDRYEGYCVELAAEIAKHVG 451
            |. |...:........:||||||||:||:||:|||:.|  .:..||:|:||||.:||..:||.:|
  Fly   480 PLNAKYVRLRPHVEFEKNRTYIVTTVLEEPYIMLKQVAFGEKLHGNNRFEGYCKDLADLLAKELG 544

Mouse   452 YSYRLEIVSDGKYGARDPDTK-AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGIS 515
            .:|.|.:|.||.||:...... .|:|||||||...||:|:|.:|||..||.||||||||||||||
  Fly   545 INYELRLVKDGNYGSEKSSAHGGWDGMVGELVRKEADIAIAAMTITAERERVIDFSKPFMSLGIS 609

Mouse   516 IMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEW--------------- 565
            ||||||.|..||||||::||:.|||:.::|:|||||:|||.||||||:||
  Fly   610 IMIKKPVKQTPGVFSFMNPLSQEIWVSVIFSYIGVSIVLFFVSRFSPHEWRLVQQQPQQSQSPDP 674

Mouse   566 --HSEEF-----------------------------------------EEGRDQTTSDQSNEFGI 587
              |.|:.                                         ..|...::|...|||.:
  Fly   675 HAHHEQLANQQPPGIIGGAPLPAPPGPPTPGAQTAAGAAALQAALSAGSPGSGGSSSAVVNEFSV 739

Mouse   588 FNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 652
            :||.||||.||||||||:||||:||||....|:|||||:||||||||||||||||||:||.|.||
  Fly   740 WNSFWFSLAAFMQQGCDLSPRSVSGRIAAASWFFFTLILISSYTANLAAFLTVERMVTPINSPED 804

Mouse   653 LAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYL 717
            ||.|||:.||||..|||.:|||||:|.:..|||.||.|.: .|||.|.:||:.|||.||||||.|
  Fly   805 LAMQTEVQYGTLLHGSTWDFFRRSQIGLHNKMWEYMNSRK-HVFVPTYDEGIKRVRNSKGKYALL 868

Mouse   718 LESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWY 782
            :||..|||:..|:||||||||.|||:||:|||||.||||:.|:|||||.|.|.|.|.||::||||
  Fly   869 VESPKNEYVNAREPCDTMKVGRNLDTKGFGIATPLGSALKDPINLAVLTLKENGELIKLRNKWWY 933

Mouse   783 DKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQ 847
            :|.||.:...| :...|.||||||||:||||||||.:::.||::|:|::||.......|..:
  Fly   934 EKAECSTHKDG-ETSHSELSLSNVAGIFYILIGGLLVSVFVAILEYCFRSRDSRSASSGSGM--- 994

Mouse   848 QSINEAIRTSTLPRNSGAGASGGSGSGENGRVVSQDFPKSMQSIPCMSHSSGMP 901
                      .|....|.|.||||....||         ||...|..:...|||
  Fly   995 ----------GLGMGLGGGMSGGSLGKANG---------SMMLGPSSAVPGGMP 1029

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.