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Protein Alignment Gria1 and GluRIID

DIOPT Version :9

Sequence 1:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus
Sequence 2:	NP_651982.1	Gene:	GluRIID / 44483	FlyBaseID:	FBgn0028422	Length:	902	Species:	Drosophila melanogaster

Alignment Length:	930	Identity:	301/930 - (32%)
Similarity:	485/930 - (52%)	Gaps:	106/930 - (11%)

- Green bases have known domain annotations that are detailed below.

Mouse    14 GAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALS----QLTEPPKLLPQIDIVNISDSFEMTYRF 74
            |....|:...:|::|.:..:...:....|..|:|    :|..|  |:.:.:.|...:|.:...:.
  Fly    23 GNAYEASSGQSIRLGLITDDATDRIRQTFEHAISVVNNELGVP--LVGETEQVAYGNSVQAFAQL 85

Mouse    75 CSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTS-NQFVLQLRPE-LQEALISII 137
            |.....||.|:||...|.|.:.|.:.|.:..:.||.|.....:: :.|.|...|| :..||..|:
  Fly    86 CRLMQSGVGAVFGPAARHTASHLLNACDSKDIPFIYPHLSWGSNPDGFNLHPSPEDIANALYDIV 150

Mouse   138 DHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVV 202
            :.::|..|::.|::...|.:|..::.....|...:..:.........|:.:.:.:.|.::..:||
  Fly   151 NQFEWSRFIFCYESAEYLKILDHLMTRYGIKGPVIKVMRYDLNLNGNYKSVLRRIRKSEDSRIVV 215

Mouse   203 DCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIM 267
            ...:..:..:|.|..::......|.||:.||.....||.::|.|.||:||.::.:     |.:
  Fly   216 VGSTTGVAELLRQAQQVGIMNEDYTYIIGNLNLHTFDLEEYKYSEANITGIRMFS-----PDQ-- 273

Mouse   268 QQWRTSDARD-----HTRVDWKRPKYTS--------ALTYDGVKVMAEAFQSL--RRQRIDISRR 317
                 .:.||     |..:....|..:.        |||||.|:|:||..:.|  :.|.::.|.|
  Fly   274 -----EEVRDLMEKLHQELGESEPVNSGSTFITMEMALTYDAVRVIAETTKHLPYQPQMLNCSER 333

Mouse   318 GN----AGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRK 378
            .:    .|....|          ..|:| :::.:.:||.:.| |...|..:|..|||::..|:.|
  Fly   334 HDNVQPDGSTFRN----------YMRSL-EIKEKTITGRIYF-EGNVRKGFTFDVIELQTSGLVK 386

Mouse   379 IGYWNEDDKF----VPAATDAQAGGDNSSVQNRTYIV-TTILEDPYVMLKKNANQFEGNDRYEGY 438
            :|.|.|...|    .|.|.:.. ..|:.|:.|:|:|| .::...||..|.::.:...||::::||
  Fly   387 VGTWEEGKDFEFQRPPQAVNFN-DIDDGSLVNKTFIVLISVATKPYASLVESIDTLIGNNQFQGY 450

Mouse   439 CVELAAEIAKHVGYSYRLEIVSDG--KYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREE 501
            .|:|..|:|..:|:::...   ||  .||:.:..|.:.:||:.|:|.||||:|:..||||..|||
  Fly   451 GVDLIKELADKLGFNFTFR---DGGNDYGSFNKTTNSTSGMLKEIVEGRADLAITDLTITSEREE 512

Mouse   502 VIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH 566
            |||||.|||:|||:|:..||||:.|.:|||:||.:.|:|:.:..||:|||:..|::.|.||.||.
  Fly   513 VIDFSIPFMNLGIAILYVKPQKAPPALFSFMDPFSSEVWLYLGIAYLGVSLCFFIIGRLSPIEWD 577

Mouse   567 S-----EEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLII 626
            :     ||.||        ..|:|.|.|||||:.||.:|||.:|:|::||.|.:..:|||||||:
  Fly   578 NPYPCIEEPEE--------LENQFTINNSLWFTTGALLQQGSEIAPKALSTRTISAIWWFFTLIM 634

Mouse   627 ISSYTANLAAFLTVERMVSPIESAEDLA-KQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKS 690
            :||||||||||||:|...|||.|.:||| .:.::.||....|||:.||..|:..::.||..|: :
  Fly   635 VSSYTANLAAFLTIENPTSPINSVKDLADNKDDVQYGAKRTGSTRNFFSTSEEPIYIKMNEYL-N 698

Mouse   691 AEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSA 755
            |.|.:.:...::|:.:| ||..|||:|:|||..|:...|: |:..|||..||.||||||..|...
  Fly   699 AHPEMLMENNQQGVDKV-KSGTKYAFLMESTSIEFNTVRE-CNLTKVGDPLDEKGYGIAMVKNWP 761

Mouse   756 LRGPVNLAVLKLSEQGVLDKLKSKWWYD--KGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLG 818
            .|...|.|:|:|.|||||.:||:|||.:  .|.|.:|  ...|..|.|.:.|::|::.:|:.|..
  Fly   762 YRDKFNKALLELQEQGVLARLKNKWWNEVGAGVCSAK--SDDDGPSELGVDNLSGIYVVLVIGSI 824

Mouse   819 LAMLVALIEFCYKSRSESKRMK-GFCLIPQQSINEAIRTSTLPRNSGAGASGGSGSGENGRVVSQ 882
            ::::::::.:||....::|..: .||....:.....||.|                 ||.|.:
  Fly   825 ISIIISILCWCYFVYKKAKNYEVPFCDALAEEFRIVIRFS-----------------ENERPL-- 870

Mouse   883 DFPKSMQSIPCMSHSSGMPL 902
               ||.|||...|.:|...:
  Fly   871 ---KSAQSIYSRSRNSSQSI 887

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.