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Protein Alignment Gria1 and Grik

DIOPT Version :9

Sequence 1:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus
Sequence 2:	NP_001262788.1	Gene:	Grik / 42476	FlyBaseID:	FBgn0038840	Length:	907	Species:	Drosophila melanogaster

Alignment Length:	937	Identity:	301/937 - (32%)
Similarity:	477/937 - (50%)	Gaps:	107/937 - (11%)

- Green bases have known domain annotations that are detailed below.

Mouse     6 AFFCTGFLGAVVGANFP----NNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQIDIVNIS- 65
            |.|..||:...:...||    ....:|.::.|........|..|:|:..|..:.| |:..|::|
  Fly    11 ASFPLGFILTSLLLAFPGCRGERTNVGLVYENTDPDLEKIFHLAISKANEENEDL-QLHGVSVSI 74

Mouse    66 ---DSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQF-----V 122
               :|||.:.:.|....:.:.|:||...........|.|.|..:.|:      ||...|     .
  Fly    75 EPGNSFETSKKLCKMLRQNLVAVFGPTSNLAARHAMSICDAKELPFL------DTRWDFGAQLPT 133

Mouse   123 LQLRPE---LQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEG 184
            :.|.|.   |..||..::....|::|..||::...|..::.:|.........||...........
  Fly   134 INLHPHPATLGVALRDMVVALGWESFTIIYESGEYLPTVRELLQMYGTAGPTVTVRRYELDLNGN 198

Mouse   185 YRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGAN 249
            ||.:.:.:....:...||......|.....|..::......|.||:.||.:..:||..::.:|.|
  Fly   199 YRNVLRRIRNADDFSFVVVGSMATLPEFFKQAQQVGLVTSDYRYIIGNLDWHTMDLEPYQHAGTN 263

Mouse   250 VTGFQLVN-------------YTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMA 301
            :||.:||:             |....|.:.:....|:               :.||.||||:::|
  Fly   264 ITGLRLVSPDSEQVQEVAKALYESEEPFQNVSCPLTN---------------SMALVYDGVQLLA 313

Mouse   302 EAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTL 366
            |.::.:..:.:.:|         .|....|.:|..:...::.:...||||.::|:.:|.||::.|
  Fly   314 ETYKHVNFRPVALS---------CNDDSAWDKGYTLVNYMKSLTLNGLTGPIRFDYEGLRTDFKL 369

Mouse   367 HVIEMKHDGIRKIGYWNEDDKFV---PAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQ 428
            .|||:...|::|||.|:.:|.|.   ||...: ...|..|:.|::::|.|.:.:||.|||:.:.:
  Fly   370 EVIELAVSGMQKIGQWSGEDGFQENRPAPAHS-LEPDMRSLVNKSFVVITAISEPYGMLKETSEK 433

Mouse   429 FEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPL 493
            .||||::||:.:||..|::|.:|:||...:..|.|||..||.|..||||:.|::..|||:.:..|
  Fly   434 LEGNDQFEGFGIELIDELSKKLGFSYTWRLQEDNKYGGIDPKTGEWNGMLREIIDSRADMGITDL 498

Mouse   494 TITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVS 558
            |:|..||..:||:.|||||||.|:.:||.|..|.:|||:.|.:.|:|:.:..||:|||:.:|::.
  Fly   499 TMTSERESGVDFTIPFMSLGIGILFRKPMKEPPKLFSFMSPFSGEVWLWLGLAYMGVSISMFVLG 563

Mouse   559 RFSPYEWHSEE--FEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWF 621
            |.||.||.:..  .||     .::..|:|...|.||||:||.:|||.:::|::.|.|.|...|||
  Fly   564 RLSPAEWDNPYPCIEE-----PTELENQFSFANCLWFSIGALLQQGSELAPKAYSTRAVAASWWF 623

Mouse   622 FTLIIISSYTANLAAFLTVERMVSPIESAEDLAK-QTEIAYGTLEAGSTKEFFRRSKIAVFEKMW 685
            ||||::||||||||||||||.:|:||..|:||:| :..:.||....|:|..||:.|....:::|:
  Fly   624 FTLILVSSYTANLAAFLTVESLVTPINDADDLSKNKGGVNYGAKIGGATFNFFKESNYPTYQRMY 688

Mouse   686 TYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIAT 750
            .:|:. .|.....|.:||:.||..|  .||:|:|||..|||.:|: |...:||..||.||||||.
  Fly   689 EFMRD-NPQYMTNTNQEGVDRVENS--NYAFLMESTTIEYITERR-CTLTQVGALLDEKGYGIAM 749

Mouse   751 PKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDK---GEC--GSKDSGSKDKTSALSLSNVAGVF 810
            .|....|..::.|||::.|||:|.|:|:|||.:|   |.|  ..:|||:    .||.:||:.|||
  Fly   750 RKNWPYRDTLSQAVLEMQEQGLLTKMKTKWWQEKRGGGACSDADEDSGA----VALEISNLGGVF 810

Mouse   811 YILIGGLGLAMLVALIEFC--YKSRSESKR-------MKGFCLIPQQSIN-EAIRTSTLPRNSGA 865
            .::..|....:.|:|:|..  .|.||:..:       :.....|.|.|.| :|::   .|:||..
  Fly   811 LVMGVGSFFGIFVSLLEMVLGVKERSDENQVSFKTELLDEIRFILQCSGNTKAVK---YPKNSSR 872

Mouse   866 GASGGSGSGENGRVVSQDFPKSMQSIP 892
            ..:.....|.:         .|:.|:|
  Fly   873 SNASSKSKGSS---------MSVDSLP 890

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.