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Protein Alignment Gria1 and KaiR1D

DIOPT Version :9

Sequence 1:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus
Sequence 2:	NP_650925.1	Gene:	KaiR1D / 42473	FlyBaseID:	FBgn0038837	Length:	853	Species:	Drosophila melanogaster

Alignment Length:	846	Identity:	335/846 - (39%)
Similarity:	512/846 - (60%)	Gaps:	63/846 - (7%)

- Green bases have known domain annotations that are detailed below.

Mouse    20 NFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLP------QIDIVNISDSFEMTYRFCSQF 78
            :.|:.|:|||||......:..|||.|:.::.....:||      ||:.::..|||....|.|...
  Fly    25 SLPDIIKIGGLFHPADDHQELAFRQAVDRINADRSILPRSKLVAQIERISPFDSFHAGKRVCGLL 89

Mouse    79 SKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPE------------LQE 131
            :.||.||||.....|.:.:.|.|..:.:..:        .|::..:||.|            |.:
  Fly    90 NIGVAAIFGPQSSHTASHVQSICDNMEIPHL--------ENRWDYRLRRESCLVNLYPHPNTLSK 146

Mouse   132 ALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEG-YRMLFQDLEKK 195
            |.:.|:.|:.|:||..||:.:.|:..||.:|.......:.:|   :...::.| ||.|.:.::..
  Fly   147 AYVDIVRHWGWKTFTIIYENNDGIVRLQELLKAHGMTPFPIT---VRQLSDSGDYRPLLKQIKNS 208

Mouse   196 KERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTD 260
            .|..:|:||.:||::.:|.|..::......:.|::.:|....::|::|:..|.|:|||:|:|  :
  Fly   209 AEAHIVLDCSTERIHEVLKQAQQIGMMSDYHSYLVTSLDLHTVNLDEFRYGGTNITGFRLIN--E 271

Mouse   261 TIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSL-RRQRIDISRRGNAGDCL 324
            .|.:.:::||...:.......:....:..:||.||.|.:.|:|...| ..|:|||......|..
  Fly   272 KIVSDVVRQWSIDEKGLLRSANLTTVRSETALMYDAVHLFAKALHDLDTSQQIDIHPISCDGQS- 335

Mouse   325 ANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNE--DDK 387
                 .|..|..:...::.|..:|||..::|:.:|.||::.|.::|:...||||||.||.  .|.
  Fly   336 -----TWQHGFSLINYMKIVEMKGLTNVIKFDHQGFRTDFMLDIVELTPAGIRKIGTWNSTLPDG 395

Mouse   388 FVPAATDAQAGGD-NSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVG 451
            .....|.:|...: .::::|:|.:|||||.:||.|.|::|....|||::|||.|:|..||:|.:|
  Fly   396 INFTRTFSQKQQEIEANLKNKTLVVTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSLG 460

Mouse   452 YSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISI 516
            ::|::::|.||.||:.:..|..||||:.||:..|||:|:|.||||..||:.:||:.|||:||:||
  Fly   461 FNYKIQLVPDGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSI 525

Mouse   517 MIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEW------HSEEFEEGRD 575
            :.:||.|..|.:||||.||:.::|:.:..||:||||:||::::|:||||      |.|:.|
  Fly   526 LYRKPIKQPPNLFSFLSPLSLDVWIYMATAYLGVSVLLFILAKFTPYEWPAYTDAHGEKVE---- 586

Mouse   576 QTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 640
                   ::|.:.|.:||::|:.||||||..|::||.|:|.|:|||||||:||||||||||||||
  Fly   587 -------SQFTLLNCMWFAIGSLMQQGCDFLPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTV 644

Mouse   641 ERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMI 705
            |||.|||||||||||||.|.||.|:.|||..|||.|||:.:::||::|:||.||||..:..||:.
  Fly   645 ERMDSPIESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNGEGVE 709

Mouse   706 RVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQ 770
            ||.|.||.||:|:|||..||:.:|. |:..:|||.||:|.||||||..|..|..:|..:|||.|:
  Fly   710 RVAKGKGSYAFLMESTSIEYVTERN-CELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEE 773

Mouse   771 GVLDKLKSKWWYDK---GECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKS 832
            |.|..||:|||.:|   |:|..:.|.|....:.|.|:||.|||.:|:||:|:|.::|:.||.:||
  Fly   774 GKLHILKTKWWKEKRGGGKCRVETSKSSSAANELGLANVGGVFVVLMGGMGVACVIAVCEFVWKS 838

Mouse   833 R 833
            |
  Fly   839 R 839

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.