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Protein Alignment Gria1 and Ir93a

DIOPT Version :9

Sequence 1:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus
Sequence 2:	NP_650924.3	Gene:	Ir93a / 42471	FlyBaseID:	FBgn0259215	Length:	868	Species:	Drosophila melanogaster

Alignment Length:	888	Identity:	168/888 - (18%)
Similarity:	315/888 - (35%)	Gaps:	236/888 - (26%)

- Green bases have known domain annotations that are detailed below.

Mouse    88 FYERRTVNMLTSFCGALHV--CFITPSFPVDTSNQFVLQL--------RPELQEALISIIDHYKW 142
            ::....|.:...|..|:.|  |..|.:|..:|....:|.:        |..|..||:..|
  Fly    82 YFSWNAVRLKKDFLAAITVTDCENTWNFYKNTQETSILLIAITDSDCPRLPLNRALMVPI----- 141

Mouse   143 QTFVYIYDADRGLSVLQRVLDTAAEK--NWQVTAVNILTTTEEGYRMLFQDL------------- 192
                    .:.|....|.:||...::  ||:...|.:..|..|...:|.:.:
  Fly   142 --------VENGDEFPQLILDAKVQQILNWKTAVVFVDQTILEENALLVKSIVHESITNHITPIS 198

Mouse   193 -------------------------------EKKKERLVVVDCESERLNAILGQIVKLEKNGIGY 226
                                           |:.:::.:|:....|       .|:::.:....:
  Fly   199 LILYEINDSLRGQQKRVALRQALSQFAPKKHEEMRQQFLVISAFHE-------DIIEIAETLNMF 256

Mouse   227 H-------YIL------ANLGFMDIDLNKFKESGANVT---------------------GFQLVN 257
            |       ::|      .:.|.:.|:|    :.|||:.                     ...|||
  Fly   257 HVGNQWMIFVLDMVARDFDAGTVTINL----DEGANIAFALNETDPNCQDSLNCTISEISLALVN 317

Mouse   258 YTDTIPARIMQQWRTSDARDHTRVDW------KRPKYTSALTY--DGVKVMAEAFQSLRRQRIDI 314
            ....|  .:.::....:..|.   :|      |:.|....|.|  :.:|..|:. .|..|.|::
  Fly   318 AISKI--TVEEESIYGEISDE---EWEAIRFTKQEKQAEILEYMKEFLKTNAKC-SSCARWRVE- 375

Mouse   315 SRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRT------NYTLHVIEMKH 373
                        .|:.||:.                   |.|.|.|.|      |.....|
  Fly   376 ------------TAITWGKS-------------------QENRKFRSTPQRDAKNRNFEFI---- 405

Mouse   374 DGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGY 438
                .||||.....||  ..:..........:|.|..:.|:...|:.:|.||:|..  ...::|.
  Fly   406 ----NIGYWTPVLGFV--CQELAFPHIEHHFRNITMDILTVHNPPWQILTKNSNGV--IVEHKGI 462

Mouse   439 CVELAAEIAKHVGYSYRLEIVSDGK--------YGARDPDTKAWNGMVG-----------ELVYG 484
            .:|:..|:::.:.:||.|...|..|        .|..:.|.     :||           |:|.|
  Fly   463 VMEIVKELSRALNFSYYLHEASAWKEEDSLSTSAGGNESDE-----LVGSMTFRIPYRVVEMVQG 522

Mouse   485 -RADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYI 548
             :..:|....|:....::..::::|......|.:.:||.:.. .::.|..|...|.|.|::...:
  Fly   523 NQFFIAAVAATVEDPDQKPFNYTQPISVQKYSFITRKPDEVS-RIYLFTAPFTVETWFCLMGIIL 586

Mouse   549 GVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGR 613
            ..:..|:.::|.:|       .:|.|....|...:.|      |:..||.:|||....|.:.|||
  Fly   587 LTAPTLYAINRLAP-------LKEMRIVGLSTVKSCF------WYIFGALLQQGGMYLPTADSGR 638

Mouse   614 IVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRR-SK 677
            :|.|.||...::::::|..||.||||..:....::....|....:|....|..|:   ||.| .:
  Fly   639 LVVGFWWIVVIVLVTTYCGNLVAFLTFPKFQPGVDYLNQLEDHKDIVQYGLRNGT---FFERYVQ 700

Mouse   678 IAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKG---KYAYLLESTMNEYIEQRKPCDTMKVGG 739
            ....|....|::.|:  ::....||.:..|::.:.   .:...|:..:..:.|:.|.|.......
  Fly   701 STTREDFKHYLERAK--IYGSAQEEDIEAVKRGERINIDWRINLQLIVQRHFEREKECHFALGRE 763

Mouse   740 NLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWY-----DKGECGSKDSGSKDKTS 799
            :...:...:..|..||....||..:..:...|.:::     |:     ..|:|..|.:..:....
  Fly   764 SFVDEQIAMIVPAQSAYLHLVNRHIKSMFRMGFIER-----WHQMNLPSAGKCNGKSAQRQVTNH 823

Mouse   800 ALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGF 842
            .:::.::.|.|.:|:.|..||:|:...||.|:....|::.:.|
  Fly   824 KVNMDDMQGCFLVLLLGFTLALLIVCGEFWYRRFRASRKRRQF 866

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.