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Protein Alignment Gria1 and Ir75c

DIOPT Version :9

Sequence 1:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus
Sequence 2:	NP_649013.3	Gene:	Ir75c / 39983	FlyBaseID:	FBgn0261401	Length:	623	Species:	Drosophila melanogaster

Alignment Length:	706	Identity:	151/706 - (21%)
Similarity:	263/706 - (37%)	Gaps:	134/706 - (18%)

- Green bases have known domain annotations that are detailed below.

Mouse   185 YRML-FQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYI-------LANL--GFMDID 239
            ||:: |..||.....|:|..|.|  :......:..|.:|||...||       |||:  .::|.|
  Fly     7 YRLIVFNLLEINLSNLMVFHCWS--IKEAFPLVEMLNQNGIFSQYIDVQNPDNLANVHKEYLDSD 69

Mouse   240 LNK---FKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMA 301
            |.:   |.:.|.:..  :||. ..:..||:..|          .:.|        |.||......
  Fly    70 LVRLGVFLDLGCDKA--ELVT-NQSSRARLYNQ----------NLHW--------LLYDEAGNFT 113

Mouse   302 EAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQR-ALQQVRFEGLTGNVQFNEKGRRTNYT 365
            :..|......:.:           |..|.:....|.:| .|..|..:|       :..|.:.|.|
  Fly   114 KLTQLFEGANLSL-----------NADVTYVSREDEERFILHDVYNKG-------SHLGGKLNIT 160

Mouse   366 L-HVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQF 429
            : ..::......:...|.:|    :......|...|.|||..|...:.::|  |....::...:|
  Fly   161 VDQTLQCNRSHCQVKEYLSE----LHLRPRLQHRMDLSSVTFRLAALVSVL--PINSSEEELLEF 219

Mouse   430 EGNDR--YEGYCVELAAEIAKHVG--YSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAV 490
            ..:||  :......:...:..|..  ..::|..:..|.:..:|    |:.|.:|.|....|::..
  Fly   220 LNSDRDSHMDSISRIGNRLIMHTQEILGFKLHYIWCGTWSVQD----AFGGAIGMLTNESAELCT 280

Mouse   491 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLF 555
            .|...:..|...:.............|.:.|..:......||:|....:|.......|...|:|:
  Fly   281 TPFVPSWNRLHYLHPMTEQAQFRAVCMFRTPHNAGIKAAVFLEPFMPSVWFAFAGLLIFAGVLLW 345

Mouse   556 LVSRFSPYEWHSEE--FEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGV 618
            ::       :|.|.  .:...|...|       :.:|...|.||...||..:.|:|..||:.
  Fly   346 MI-------FHLERHWMQRCLDFIPS-------LLSSCLISFGAACIQGSYLMPKSAGGRLA--- 393

Mouse   619 WWFFTLIIISSYTANLAAFLTVERMV-SPIESAEDLAKQTEIAYGTLEAG-----STKEFF---R 674
              |..:::.|....|....:.|..:: ||:.|  ::....::|..:|:.|     .||.:.   .
  Fly   394 --FIAVMLTSFLMYNYYTSIVVSTLLGSPVRS--NIRTIQQLADSSLDVGFDTVPFTKTYLVSSP 454

Mouse   675 RSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLE-STMNEYIEQ----RKPCDT 734
            |..|....|.....|....||:: :.|||:||||...| :.|..| |.|..::|:    |:..|.
  Fly   455 RPDIRSLYKQKVESKRDPNSVWL-SPEEGVIRVRDQPG-FVYTSEASFMYHFVEKHYLPREISDL 517

Mouse   735 MKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTS 799
            .::....:|..||: ....|..|..:....:::.|.|:..| :|:::            ||.|..
  Fly   518 NEIILRPESAVYGM-VHLNSTYRQLLTQLQVRMLETGITSK-QSRFF------------SKTKLH 568

Mouse   800 ALSLSNV--------AGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQ 847
            ..|.|.|        |.:|..|:....||:|:.::|.|: :|...|:..  .:|||
  Fly   569 TFSNSFVIQVGMEYAAPLFISLLVAYFLALLILILEICW-ARYAKKKFS--TIIPQ 621

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.