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Protein Alignment Gria1 and Ir41a

DIOPT Version :9

Sequence 1:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus
Sequence 2:	NP_995744.4	Gene:	Ir41a / 2768714	FlyBaseID:	FBgn0040849	Length:	648	Species:	Drosophila melanogaster

Alignment Length:	472	Identity:	95/472 - (20%)
Similarity:	172/472 - (36%)	Gaps:	88/472 - (18%)

- Green bases have known domain annotations that are detailed below.

Mouse   402 SSVQNRTYIVTTILEDPYVMLKKN------------ANQFEGNDRYEGYCVELAAEIAKHVGYSY 454
            :::|.|..|:......||.::|.|            .:.|: |...:|....:.....:....:.
  Fly   206 NNLQGREVIIAGFDYPPYTVIKHNMSTNAQDMGVSGESDFK-NVYIDGTETRIVLNFCEQFNCTI 269

Mouse   455 RLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIK 519
            :::..:...:|...|:... :|.:|.|:..:||:.:..:.........:|.|...:..||:.::.
  Fly   270 QIDSSAANDWGKVYPNMSG-DGALGMLINRKADICIGAMYSWYEDYTYLDLSMYLVRSGITCLVP 333

Mouse   520 KPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNE 584
            .|.:....... |:|....:|..|:......:..|.|..:.....:....:.||....||
  Fly   334 APLRLTSWYLP-LEPFKETLWAAILLCLCAEATGLVLAYKSEQALYVLPGYREGWWTCTS----- 392

Mouse   585 FGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 649
            ||:..:  |.|  |:.|..:....||:.|::....:...|||.|.|...||:.||:..|    :.
  Fly   393 FGVCTT--FKL--FISQSGNSKAYSLTVRVLLFACFLNDLIITSIYGGGLASILTIPSM----DE 449

Mouse   650 AEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIR-VRKSKGK 713
            |.|..              |:..|.|.:.|...:.|.   ||     :|.::|.::: :..:...
  Fly   450 AADTV--------------TRLRFHRLQWAANSEAWV---SA-----IRASDEALVKDILYNFHI 492

Mouse   714 YA--YLLESTMNEYIE-----QRKPCDTMKVGGNLDSKG--------------YGIA-TPKGSAL 756
            |:  .||....::::.     :|.|.....:|..|..:.              |.:| .|:...|
  Fly   493 YSDDELLRLAQDQHMRIGFTVERLPFGHFAIGNYLGPQAIDQLVIMKDDIYFQYTVAFVPRLWPL 557

Mouse   757 RGPVNLAVLKLSEQG---------VLDKLKSKWWYDKGE--CGSKDSGSKDKTSALSLSNVAGVF 810
            ...:|..:......|         |.|.|..|......|  .|:||.|    ...|.:||.||..
  Fly   558 LDKLNTLIYSWHSSGFDKYWEYRVVADNLNLKIQQQVQETMTGTKDIG----PVPLGMSNFAGFI 618

Mouse   811 YILIGGLGLAMLVALIE 827
            .:.|.|..:|.|..|:|
  Fly   619 IVWILGSAIATLTFLLE 635

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.