Protein Alignment PPM1N and alph

DIOPT Version :10

• Sequence 1: XP_047294180.1
• Gene: PPM1N / 147699
• HGNCID: 26845
• Length: 448
• Species: Homo sapiens
• Sequence 2: NP_651701.1
• Gene: alph / 43481
• FlyBaseID: FBgn0086361
• Length: 374
• Species: Drosophila melanogaster
• Alignment Length: 353
• Identity: 142/353 - (40%)
• Similarity: 200/353 - (56%)
• Gaps: 21/353 - (5%)

Human    46 LTAPRRAQRPHGGAEASGGLRFGASAAQGWRARMEDAHCTWLSLPGLPPGWALFAVLDGHGGARA 110
            |..|:.|:  |........|.||.|:.||||:.||||:.....|....|.|:.|||.|||.|.:.
  Fly     5 LDKPKTAK--HNDEGEGNKLLFGVSSMQGWRSEMEDAYYARAGLGDALPDWSFFAVFDGHAGCKV 67

Human   111 ARFGARHLPGHVLQELGPEPSEPEGVR----EALRRAFLSADERLRSLWPRV-----ETGGCTAV 166
            :...|:||...::       |..|.:.    :.:|..||..||.:|.| |..     :.||.|||
  Fly    68 SEHCAKHLLESII-------STEEFIGGDHVKGIRTGFLRIDEVMREL-PEFTRESEKCGGTTAV 124

Human   167 VLLVSPRFLYLAHCGDSRAVLSRAGAVAFSTEDHRPLRPRERERIHAAGGTIRRRRVEGSLAVSR 231
            ...|....:|:|:||||||||.|.|...|:|:||:|:.|.|:|||:.|||::..:||.|:|||||
  Fly   125 CAFVGLTQVYIANCGDSRAVLCRQGVPVFATQDHKPILPEEKERIYNAGGSVMIKRVNGTLAVSR 189

Human   232 ALGDFTYKEAPGRPPELQLVSAEPEVAALARQAEDEFMLLASDGVWDTVSGAALAGLVASRLRLG 296
            ||||:.:|....:....||||.|||:...:||..|||::||.||:||.:|...:...:.||:|:.
  Fly   190 ALGDYDFKNVKEKGQCEQLVSPEPEIFCQSRQDSDEFLVLACDGIWDVMSNEDVCSFIHSRMRVT 254

Human   297 LAPELLCAQLLDTCLCKGSLDNMTCILVCFPGAPRPSEEAIRRELALDAALGCRIAELCASAQKP 361
            .....:..|::||||.|||.|||:.|::.|||||:|:||||..|..|:..:. :|......:.|.
  Fly   255 SNLVSIANQVVDTCLHKGSRDNMSIIIIAFPGAPKPTEEAIEAEHRLEKQIE-KITRDEIESSKI 318

Human   362 PSLNTVFRTLAS-EDIPDLPPGGGLDCK 388
            .....:.:.|.: :||..|||||||..|
  Fly   319 TDYVDLLKCLQNRDDIEGLPPGGGLQSK 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPM1N	XP_047294180.1	PP2Cc	66..326	CDD:238083	112/268 (42%)
		PP2C_C	320..389	CDD:429684	26/70 (37%)
alph	NP_651701.1	PP2Cc	24..284	CDD:238083	112/267 (42%)
		PP2C_C	278..355	CDD:429684	26/70 (37%)