Protein Alignment PPM1N and Nil

DIOPT Version :10

• Sequence 1: XP_047294180.1
• Gene: PPM1N / 147699
• HGNCID: 26845
• Length: 448
• Species: Homo sapiens
• Sequence 2: NP_651472.2
• Gene: Nil / 43185
• FlyBaseID: FBgn0039421
• Length: 371
• Species: Drosophila melanogaster
• Alignment Length: 341
• Identity: 132/341 - (38%)
• Similarity: 195/341 - (57%)
• Gaps: 12/341 - (3%)

Human    50 RRAQRPHGGAEASGGLRFGASAAQGWRARMEDAHCTWLSLPGLPPGWALFAVLDGHGGARAARFG 114
            ::||..||     .|||:..|:.||||..|||:|.....|......|:.|||.|||.|::.:...
  Fly    16 KQAQEGHG-----NGLRYCVSSMQGWRLEMEDSHSAACRLKDPFATWSYFAVFDGHAGSQISLHC 75

Human   115 ARHLPGHVLQELGPEPSEPEGVREALRRAFLSADERLRSLWPRVETGGCTAVVLLVSPRFLYLAH 179
            |.||...:|:.   |..........:|..||..||.:|.|: ..:.||.||:.:.|||..:||.:
  Fly    76 AEHLMSTILES---ESFSKHKYEAGIREGFLQLDEDMRKLY-HDQQGGSTAICVFVSPDKIYLVN 136

Human   180 CGDSRAVLSRAGAVAFSTEDHRPLRPRERERIHAAGGTIRRRRVEGSLAVSRALGDFTYKEAPGR 244
            |||||||:||.||...||.||:|..|:|:|||..|||::..:|:.|:||||||.||:.:|....:
  Fly   137 CGDSRAVISRNGAAVISTIDHKPFSPKEQERIQNAGGSVMIKRINGTLAVSRAFGDYDFKNDGSK 201

Human   245 PPELQLVSAEPEVAALARQAEDEFMLLASDGVWDTVSGAALAGLVASRLRLGLAPELLCAQLLDT 309
            .|..|:||.||::....|...|||:::|.||:||.::.:.:...:.|||.:.....::...:||.
  Fly   202 SPVDQMVSPEPDIIVCNRSEHDEFIVVACDGIWDVMTSSEVCEFIRSRLLVTYDLPMIVNSVLDI 266

Human   310 CLCKGSLDNMTCILVCFPGAPRPSEEAIRRELALDAALGCRIAELCASAQKPPSLNTVFRTL--A 372
            ||.|||.||||.:|:..||||:...:|::.|.:||..: .:|.:......:.....|:.|.:  .
  Fly   267 CLHKGSRDNMTLLLLLLPGAPKVDMDAVKAERSLDQTI-VQITKEVIEKHEIHDFETLIRLMKRM 330

Human   373 SEDIPDLPPGGGLDCK 388
            :.:||:|||||||..|
  Fly   331 AINIPNLPPGGGLYAK 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPM1N	XP_047294180.1	PP2Cc	66..326	CDD:238083	105/259 (41%)
		PP2C_C	320..389	CDD:429684	23/71 (32%)
Nil	NP_651472.2	PP2Cc	27..277	CDD:238083	102/253 (40%)
		PP2C_C	284..355	CDD:429684	21/64 (33%)