Protein Alignment PPM1N and CG17746

DIOPT Version :10

• Sequence 1: XP_047294180.1
• Gene: PPM1N / 147699
• HGNCID: 26845
• Length: 448
• Species: Homo sapiens
• Sequence 2: NP_647794.1
• Gene: CG17746 / 38400
• FlyBaseID: FBgn0035425
• Length: 371
• Species: Drosophila melanogaster
• Alignment Length: 281
• Identity: 115/281 - (40%)
• Similarity: 162/281 - (57%)
• Gaps: 14/281 - (4%)

Human    66 RFGASAAQGWRARMEDAHCTWLSLPGLPPGWALFAVLDGHGGARAARFGARHLPGHVLQELGPEP 130
            |.|:|..||||..|||:|...||||. .||.|.|||.||||||..|::..:||..:||:    .|
  Fly    23 RVGSSCMQGWRINMEDSHTHILSLPD-DPGAAFFAVYDGHGGATVAQYAGKHLHKYVLK----RP 82

Human   131 SEPEGVREALRRAFLSAD-ERLRSLWPRVETGGCTAVVLLVSPRFLYLAHCGDSRAVLSRAGAVA 194
            ...:.:.:||::.||..| ..||:.....:..|.||||:||....||.|:.|||||:....|.:.
  Fly    83 EYNDNIEQALQQGFLDIDYVMLRNKTCGDQMAGSTAVVVLVKDNKLYCANAGDSRAIACVNGQLE 147

Human   195 FSTEDHRPLRPRERERIHAAGGTIRRRRVEGSLAVSRALGDFTYKEAPGRPPELQLVSAEPEVAA 259
            ..:.||:|....|.:||...||.:...||.|:||:||||||:.:|. ..:.||.|:|:|.|:|..
  Fly   148 VLSLDHKPNNEAESKRIIQGGGWVEFNRVNGNLALSRALGDYVFKH-ENKKPEDQIVTAFPDVET 211

Human   260 LARQAEDEFMLLASDGVWDTVSGAALAGLVASRLRLGLAPELLCAQLLDTCL---CK-GSL--DN 318
            .....:.||::||.||:||.:|.|.:.....:|:.:|:.||.:|.:|::.||   |: |.|  ||
  Fly   212 RKIMDDWEFIVLACDGIWDVMSNAEVLEFCRTRIGMGMFPEEICEELMNHCLAPDCQMGGLGGDN 276

Human   319 MTCILVCFPGAPRPSEEAIRR 339
            ||.:|||.... ||..:.|.|
  Fly   277 MTVVLVCLLHG-RPYSDLIAR 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPM1N	XP_047294180.1	PP2Cc	66..326	CDD:238083	110/266 (41%)
		PP2C_C	320..389	CDD:429684	8/20 (40%)
CG17746	NP_647794.1	PP2Cc	22..284	CDD:238083	110/266 (41%)