DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ptgdr2 and TkR86C

DIOPT Version :9

Sequence 1:NP_034092.1 Gene:Ptgdr2 / 14764 MGIID:1330275 Length:382 Species:Mus musculus
Sequence 2:NP_001097741.1 Gene:TkR86C / 41286 FlyBaseID:FBgn0004841 Length:555 Species:Drosophila melanogaster


Alignment Length:380 Identity:89/380 - (23%)
Similarity:165/380 - (43%) Gaps:68/380 - (17%)


- Green bases have known domain annotations that are detailed below.


Mouse    36 LLHGLASLLGLVENGLILFVV-GCRMRQTVVTTWVLHLALSDLLAAASLPFFTYFLAVGHSWELG 99
            ::.||...:.:..||::|::| |.|..:||...::|:|:::|||.::....|.:...:...|..|
  Fly    88 IIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFG 152

Mouse   100 TTFCKLHSSVFFLNMFASGFLLSAISLDRCLQVVRPVWAQNHRTVAVAHRVCLML-WALAVLNTI 163
            :.:|.:::.|..:.:..|.|.|.|||.||.:.:|.|:   ..||.....|:.|:| |||:.:.:.
  Fly   153 SIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPL---KRRTSRRKVRIILVLIWALSCVLSA 214

Mouse   164 PYFVFRDTIPRLDGRIMCYYN-------LLLWNPGPDRDTTCDYRQKALAVSKFLLAFMVPLAII 221
            |..::...:.:      .|||       .::|..|....:..||....:.:   :|.:.:|:.::
  Fly   215 PCLLYSSIMTK------HYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIIL---VLTYGIPMIVM 270

Mouse   222 ------------ASSHVAVSLRLHHRGRQRTGRFVRLVAAIVVAFVLCWGPYHIFSLLEARAHSV 274
                        .|..:..:........:...:.||:..|||..|.:||.|||:|.:.....:.|
  Fly   271 LICYSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQV 335

Mouse   275 TTLRQLASRGLPFVTSLAFFNSVVNPLLYVFTCPDMLYKLRRSLRAVLESVLV----------ED 329
            .:.:.:....|.|.. ||..|::||||:|        |.:.:..|...:.::.          .|
  Fly   336 ASTKYVQHMYLGFYW-LAMSNAMVNPLIY--------YWMNKRFRMYFQRIICCCCVGLTRHRFD 391

Mouse   330 SDQS-------------GGLRNRRRRASSTATPASTLL--LADRIPQLRP-TRLI 368
            |.:|             ||........:|:.....|||  ||..:.|.:| |:|:
  Fly   392 SPKSRLTNKNSSNRHTRGGYTVAHSLPNSSPPTTQTLLAVLAQTLTQPKPQTQLL 446

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ptgdr2NP_034092.1 7tm_GPCRs 32..314 CDD:391938 73/298 (24%)
TM helix 1 34..58 CDD:341315 6/22 (27%)
TM helix 2 66..87 CDD:341315 5/20 (25%)
TM helix 3 104..126 CDD:341315 6/21 (29%)
TM helix 4 149..165 CDD:341315 6/16 (38%)
TM helix 5 203..226 CDD:341315 3/34 (9%)
TM helix 6 241..266 CDD:341315 12/24 (50%)
TM helix 7 282..307 CDD:341315 10/24 (42%)
Involved in the recycling of CRTH2. /evidence=ECO:0000250 329..332 2/2 (100%)
TkR86CNP_001097741.1 7tm_4 92..376 CDD:304433 73/304 (24%)
7tm_1 100..363 CDD:278431 69/275 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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