Protein Alignment Bscl2 and Seipin

DIOPT Version :9

• Sequence 1: NP_001129536.1
• Gene: Bscl2 / 14705
• MGIID: 1298392
• Length: 443
• Species: Mus musculus
• Sequence 2: NP_570012.1
• Gene: Seipin / 31245
• FlyBaseID: FBgn0040336
• Length: 370
• Species: Drosophila melanogaster
• Alignment Length: 358
• Identity: 117/358 - (32%)
• Similarity: 195/358 - (54%)
• Gaps: 40/358 - (11%)

Mouse    82 GRARRLMLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFHYRTDCDSSTASLCSFPV 146
            |..|.|:|:.|::...::|::|::||:|.:|||.|||.:||..|||..::|..::||.  |:||.
  Fly    46 GTVRELVLRLGLIAFAVVLIIWLAVFMYAAFYYVYMPAISHTRPVHMQFKTCLETSTP--CTFPH 108

Mouse   147 ANVSLAKSGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTVSCYTRGGRIISTSSRSVMLHY 211
            |:|||.|  :.::||.||.|:|.:.:::||||.|.:||||:|..........:...|.||.|:.|
  Fly   109 AHVSLTK--KQQLLMVGQAYKVIVNIDMPESPQNLELGMFMVCAEMRDYDSMLRGHSCRSAMMRY 171

Mouse   212 RSQLLQVLDTLLFSSLLLFGFAEQKQLLEVELYSDYRENSYVPTTGAIIEIHSKRIQMYGAYLRI 276
            ||.|::::.|.:.|.|.:.|:.|:.|.:.||::|.|.|....|.|...:||.|::||.|...|.|
  Fly   172 RSPLIRMISTWVLSPLYVLGWKEEFQQVPVEIFSRYLEERQHPITDVYVEIQSQKIQFYTVTLHI 236

Mouse   277 HAHFTGLRYLLYNFPMTCAFVGVASNFTFLSVIVLFSYMQWVWGAVWPRHRFSLQVNIRQRDNSH 341
            .|.||||||:::|:|:..|.|.:::|..|:.|:.|.|:..|. .|.|   ..|:|:...:...|
  Fly   237 VADFTGLRYIMFNWPVLSAIVAISTNLFFILVVFLLSWYHWS-DAKW---LHSVQIKYARLTKS- 296

Mouse   342 HGAPRRISRHQPGQESTQQSDVTEDGESPEDPSGTEGQLSEEEKPEKRPLNGEEEQEPEASDGSW 406
                     .:||...::.|.:.:|.:.         .::..:|.:...:.|:     ..||...
  Fly   297 ---------LEPGVIHSKASSLRDDDDD---------LVAYSDKSDIADVGGD-----TLSDVDA 338

Mouse   407 EDAALLTEANPPTSASASALAPETLGSLRQRPT 439
            :|..|:.:     |.|....:|:   :||:|||
  Fly   339 DDLVLVKK-----SRSGKRESPD---ALRKRPT 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bscl2	NP_001129536.1	Seipin	99..302	CDD:284243	83/202 (41%)
		PHA00666	352..>417	CDD:222808	10/64 (16%)
Seipin	NP_570012.1	Seipin	63..262	CDD:284243	83/202 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832328
Domainoid	1	1.000	170	1.000	Domainoid score	I3771
eggNOG	1	0.900	-	-		E1_KOG4200
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	195	1.000	Inparanoid score	I3816
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004864
OrthoInspector	1	1.000	-	-		oto93964
orthoMCL	1	0.900	-	-		OOG6_104060
Panther	1	1.100	-	-	LDO	PTHR21212
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R150
SonicParanoid	1	1.000	-	-		X4543
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.780