Protein Alignment Gnb2 and Gbeta5

DIOPT Version :10

• Sequence 1: NP_034442.1
• Gene: Gnb2 / 14693
• MGIID: 95784
• Length: 340
• Species: Mus musculus
• Sequence 2: NP_572452.1
• Gene: Gbeta5 / 31744
• FlyBaseID: FBgn0030011
• Length: 358
• Species: Drosophila melanogaster
• Alignment Length: 340
• Identity: 164/340 - (48%)
• Similarity: 241/340 - (70%)
• Gaps: 3/340 - (0%)

Mouse     3 ELEQLRQEAEQLRNQIRDARKACGDSTLTQITAGLDPVGRIQMRTRRTLRGHLAKIYAMHWGTDS 67
            ::..|.:|||.|:.::.:.|:...|..|:.|...|:.:..:.::.|:.|:||.||:....|..|.
  Fly    18 KMASLVREAENLKTKLEEERQKLNDVNLSNIAERLEQIAYVNIKPRKVLKGHQAKVLCTDWSPDK 82

Mouse    68 RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGN 132
            |.::|:||||:|||||::||||.||:.:.::|:|.|||||||||||||||||..::|.:.:.|..
  Fly    83 RHIISSSQDGRLIIWDAFTTNKEHAVTMPTTWIMACAYAPSGNFVACGGLDNKVTVYPITSDEEM 147

Mouse   133 VRVSRELPGHTGYLSCCRFLD-DNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPD- 195
            ....|.:..||.|:|||.:.: |.||:|.|||:||||||:|:||....|.|||||||::.|||:
  Fly   148 AAKKRTVGTHTSYMSCCIYPNSDQQILTGSGDSTCALWDVESGQLLQSFHGHSGDVMAIDLAPNE 212

Mouse   196 -GRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQ 259
             |.|||||:||....:||:|.....|:|.||:||:|:|.|.|.|.|..|||||::|||:|:|||:
  Fly   213 TGNTFVSGSCDRMAFIWDMRSGHVVQSFEGHQSDVNSVKFHPCGDAIATGSDDSSCRLYDMRADR 277

Mouse   260 ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDG 324
            |:.:::.::||.|:.||.||.|||||.|||:|:..|:||.:|.:|..:|.||:|:|||:.|:.||
  Fly   278 EVAVFAKESIIFGVNSVDFSVSGRLLFAGYNDYTVNLWDTLKSERVCLLYGHENKVSCVQVSPDG 342

Mouse   325 MAVATGSWDSFLKIW 339
            .|::|||||..:::|
  Fly   343 TALSTGSWDYTIRVW 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gnb2	NP_034442.1	WD40	48..340	CDD:238121	154/295 (52%)
		WD 1	53..83		15/29 (52%)
		WD40 repeat	58..95	CDD:293791	19/36 (53%)
		WD 2	95..125		19/29 (66%)
		WD40 repeat	101..141	CDD:293791	21/39 (54%)
		WD 3	141..170		17/29 (59%)
		WD40 repeat	146..181	CDD:293791	19/35 (54%)
		WD 4	182..212		18/31 (58%)
		WD40 repeat	188..223	CDD:293791	16/36 (44%)
		WD 5	224..254		18/29 (62%)
		WD40 repeat	229..265	CDD:293791	19/35 (54%)
		WD 6	268..298		17/29 (59%)
		WD40 repeat	273..309	CDD:293791	18/35 (51%)
		WD 7	310..340		16/30 (53%)
		WD40 repeat	315..339	CDD:293791	12/23 (52%)
Gbeta5	NP_572452.1	WD40	62..358	CDD:238121	154/296 (52%)
		WD40 repeat	73..110	CDD:293791	19/36 (53%)
		WD40 repeat	116..156	CDD:293791	21/39 (54%)
		WD40 repeat	161..197	CDD:293791	19/35 (54%)
		WD40 repeat	204..241	CDD:293791	16/36 (44%)
		WD40 repeat	247..283	CDD:293791	19/35 (54%)
		WD40 repeat	291..327	CDD:293791	18/35 (51%)
		WD40 repeat	333..357	CDD:293791	12/23 (52%)