Protein Alignment Gnao1 and Galphao

DIOPT Version :9

• Sequence 1: NP_001106855.1
• Gene: Gnao1 / 14681
• MGIID: 95775
• Length: 354
• Species: Mus musculus
• Sequence 2: NP_523684.2
• Gene: Galphao / 36104
• FlyBaseID: FBgn0001122
• Length: 354
• Species: Drosophila melanogaster
• Alignment Length: 354
• Identity: 287/354 - (81%)
• Similarity: 317/354 - (89%)
• Gaps: 0/354 - (0%)

Mouse     1 MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGED 65
            |||..|||||||..||:.||:|||||||.||||:||||||||||||||||||||||||.||:.||
  Fly     1 MGCAQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAED 65

Mouse    66 VKQYKPVVYSNTIQSLAAIVRAMDTLGVEYGDKERKTDSKMVCDVVSRMEDTEPFSAELLSAMMR 130
            .|||:|||||||||||.||:|||.||.::|.:.||::|:|||.||..||.||||||.|||:||.|
  Fly    66 FKQYRPVVYSNTIQSLVAILRAMPTLSIQYSNNERESDAKMVFDVCQRMHDTEPFSEELLAAMKR 130

Mouse   131 LWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAGDYQPTEQDILRTRVKTTGIVETHFTFKNL 195
            ||.|:|:||||:||.||||||||||:||.|||:||.|||||||||||||||||||||.||:||||
  Fly   131 LWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSFKNL 195

Mouse   196 HFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLKLFDSICNNKWF 260
            :|:|||||||||||||||||||||||||||||:|.||||||||||||||.|||||||||||||||
  Fly   196 NFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNNKWF 260

Mouse   261 TDTSIILFLNKKDIFEEKIKKSPLTICFPEYTGPSAFTEAVAHIQGQYESKNKSAHKEVYSHVTC 325
            |||||||||||||:|||||:|||||||||||||...:.||.|:||.|:|:||||..||:|.|:||
  Fly   261 TDTSIILFLNKKDLFEEKIRKSPLTICFPEYTGGQEYGEAAAYIQAQFEAKNKSTSKEIYCHMTC 325

Mouse   326 ATDTNNIQFVFDAVTDVIIAKNLRGCGLY 354
            ||||||||||||||||||||.||||||||
  Fly   326 ATDTNNIQFVFDAVTDVIIANNLRGCGLY 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gnao1	NP_001106855.1	G_alpha	14..352	CDD:214595	273/337 (81%)
		G-alpha	34..348	CDD:206639	254/313 (81%)
Galphao	NP_523684.2	G-alpha	34..348	CDD:206639	254/313 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834824
Domainoid	1	1.000	550	1.000	Domainoid score	I253
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39203
Inparanoid	1	1.050	591	1.000	Inparanoid score	I983
Isobase	1	0.950	-	0	Normalized mean entropy	S412
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D406662at33208
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	1	1.000	-	-		oto92511
orthoMCL	1	0.900	-	-		OOG6_100285
Panther	1	1.100	-	-	LDO	PTHR10218
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R506
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.850