Protein Alignment Gna11 and Galphao

DIOPT Version :10

• Sequence 1: NP_034431.1
• Gene: Gna11 / 14672
• MGIID: 95766
• Length: 359
• Species: Mus musculus
• Sequence 2: NP_523684.2
• Gene: Galphao / 36104
• FlyBaseID: FBgn0001122
• Length: 354
• Species: Drosophila melanogaster
• Alignment Length: 353
• Identity: 173/353 - (49%)
• Similarity: 235/353 - (66%)
• Gaps: 9/353 - (2%)

Mouse     7 MACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEED 71
            |.|..|.|.:.:...:..||:.|:.|...|.:::||||||.|||||||.:|||:|||.:|::.||
  Fly     1 MGCAQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAED 65

Mouse    72 KRGFTKLVYQNIFTAMQAMVRAMETLKILYKYEQNKANALLIREV-----DVEKVTTFEHQYVNA 131
            .:.:..:||.|...::.|::|||.||.|.|...:.:::|.::.:|     |.|   .|..:.:.|
  Fly    66 FKQYRPVVYSNTIQSLVAILRAMPTLSIQYSNNERESDAKMVFDVCQRMHDTE---PFSEELLAA 127

Mouse   132 IKTLWSDPGVQECYDRRREFQLSDSAKYYLTDVDRIATVGYLPTQQDVLRVRVPTTGIIEYPFDL 196
            :|.||.|.|||||:.|..|:||:|||||:|.|:||:....|.||:||:||.||.||||:|..|..
  Fly   128 MKRLWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSF 192

Mouse   197 ENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITY 261
            :|:.|::.|||||||||:|||||||:||:|:|.||:|||||||.|.:..|||:||..||.:|...
  Fly   193 KNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNN 257

Mouse   262 PWFQNSSVILFLNKKDLLEDKILHSHLVDYFPEFDGPQRDAQAAREFILKMFVDLNPDSDKIIYS 326
            .||.::|:|||||||||.|:||..|.|...|||:.|.|...:|| .:|...|...|..:.|.||.
  Fly   258 KWFTDTSIILFLNKKDLFEEKIRKSPLTICFPEYTGGQEYGEAA-AYIQAQFEAKNKSTSKEIYC 321

Mouse   327 HFTCATDTENIRFVFAAVKDTILQLNLK 354
            |.||||||.||:|||.||.|.|:..||:
  Fly   322 HMTCATDTNNIQFVFDAVTDVIIANNLR 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gna11	NP_034431.1	G-alpha	40..353	CDD:206639	162/317 (51%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	41..54		11/12 (92%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	178..186		5/7 (71%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	201..210		5/8 (63%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	270..277		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	329..334		4/4 (100%)
Galphao	NP_523684.2	G-alpha	34..348	CDD:206639	162/317 (51%)