Protein Alignment Glra4 and SecCl

DIOPT Version :9

• Sequence 1: NP_034427.2
• Gene: Glra4 / 14657
• MGIID: 95750
• Length: 456
• Species: Mus musculus
• Sequence 2: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 523
• Identity: 144/523 - (27%)
• Similarity: 248/523 - (47%)
• Gaps: 104/523 - (19%)

Mouse     3 TLVPASLFLLLWTLPGKVLLSVALAKEDVKSGLKGSQPMSPSDFLDKLMGRTSGYDARIRP---- 63
            ||:   |.|.:||..|      ..|:|:....:..:..:..:..:.:|. ....||...||
  Fly    13 TLI---LVLSIWTSVG------VKAEEEECPSMADAGSLQQTQLIQRLT-HVCRYDRLERPFEYD 67

Mouse    64 -NFKGPPVNVTCNIFINSFGSVTETTMDYRVNVFLRQQWNDPRLAYREY-PDDSLDLDPSMLDSI 126
             :.|..|:.|...|::....::....:.::::..|:.::.|.||||:.: ..|::.....:.:.:
  Fly    68 SDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHLSERL 132

Mouse   127 WKPDLFFANEKGANFHEVTTDNK--LLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQL 189
            |.|.:|||||:.::.  :.||.|  |..:...|||:.|.|:...|.|.|:.:.||.|.|.|:..|
  Fly   133 WLPHIFFANERESSI--LGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVL 195

Mouse   190 ESFGYTMNDLMFEW-----LEDAPAVQVAEGLTLPQF-----ILRDEKD---LGYCTKHYNTGKF 241
            ||:.|..:||:.||     :...|.:::.| ..:.||     |::.:.|   .|....:|::..|
  Fly   196 ESWMYNTSDLILEWEPHTPISFDPEMRLTE-YNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSF 259

Mouse   242 TCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRA 306
            |     .:|:|::|:||:..|:||::||.:||||||:..||:|.|:.||.:|:|:..|.||....
  Fly   260 T-----VNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSK 319

Mouse   307 SLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFMRLRR-------------RQRRQ 358
            :||||||:|..::|...|..|:|.:|:|:|.||.:.|: ||.:.|::             |..|:
  Fly   320 NLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIWRR-KENIELKKVNSKYIIKSTLTPRPARR 383

Mouse   359 RMEEDIIRESRFYFRGYGLGHC------------LQARDGGPMEGSSIY-SPQPPTPLLK----E 406
            ::...:..|||       ...|            ::..:|...:|.:.| :..|..|:::    |
  Fly   384 QIGGSLSNESR-------ARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAE 441

Mouse   407 GETM----------RKLYVDRAKR-----------------IDTISRAVFPFTFLVFNIFYWVVY 444
            .:|:          ..:.||:.|:                 ||..||.:||..||.||..||...
  Fly   442 ADTVSICSARTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWTFV 506

Mouse   445 KVL 447
            .||
  Fly   507 YVL 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glra4	NP_034427.2	LIC	9..444	CDD:273305	140/512 (27%)
		Strychnine-binding. /evidence=ECO:0000250|UniProtKB:O93430	236..241		1/4 (25%)
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	133/478 (28%)
		Neur_chan_LBD	44..267	CDD:280998	60/231 (26%)
		Neur_chan_memb	275..503	CDD:280999	68/235 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910