Protein Alignment TTBK2 and CG7094

DIOPT Version :10

• Sequence 1: XP_005254228.1
• Gene: TTBK2 / 146057
• HGNCID: 19141
• Length: 1250
• Species: Homo sapiens
• Sequence 2: NP_609851.2
• Gene: CG7094 / 35065
• FlyBaseID: FBgn0032650
• Length: 390
• Species: Drosophila melanogaster
• Alignment Length: 227
• Identity: 78/227 - (34%)
• Similarity: 119/227 - (52%)
• Gaps: 19/227 - (8%)

Human    88 GCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSN 152
            ||.:|  :|.:||.|.|.:|.:|.....| .|::.|.|.|..|:|..||.:|..||:||||||.|
  Fly    90 GCEKN--YNAMVMDLLGPSLEELFNLCKR-RFSLKTVLMLTDQLLMRIECVHERGFIHRDIKPDN 151

Human   153 FAMGRFPSTCRKCYMLDFGLARQFTNSCGDVR-PPRAVAGFRGTVRYASINAHRNREMGRHDDLW 216
            |.|| ....|.|.|::||||::::.:...::. |.|......||||||||||....|..|.||:.
  Fly   152 FLMG-LDRHCNKLYLIDFGLSKRYKDIESEIHIPYRTDRNLTGTVRYASINAQIGVEQSRRDDME 215

Human   217 SLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRL----------MLKHLPPEFSIFLDHISSL 271
            |:.|.|:.|.:|:|||:.|    ...:.|::|:..|          :.|..|.||.:.:.::.:|
  Fly   216 SMSYCLMYFNLGKLPWQGI----TAANKKQKYEKILEKKTSVTIAQLCKGFPSEFCLLMTYVRNL 276

Human   272 DYFTKPDYQLLTSVFDNSIKTFGVIESDPFDW 303
            .:...||:..|..:|....::........:||
  Fly   277 GFKEPPDHTYLRQIFRILFRSLNHHYDYIYDW 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTBK2	XP_005254228.1	Protein Kinases, catalytic domain	75..287	CDD:473864	75/209 (36%)
CG7094	NP_609851.2	STKc_CK1	26..291	CDD:270918	75/208 (36%)