Protein Alignment CSNK2A2 and p38a

DIOPT Version :10

• Sequence 1: NP_001887.1
• Gene: CSNK2A2 / 1459
• HGNCID: 2459
• Length: 350
• Species: Homo sapiens
• Sequence 2: NP_477163.1
• Gene: p38a / 42866
• FlyBaseID: FBgn0015765
• Length: 366
• Species: Drosophila melanogaster
• Alignment Length: 341
• Identity: 103/341 - (30%)
• Similarity: 188/341 - (55%)
• Gaps: 46/341 - (13%)

Human    21 SREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEA-INITNNERVVVKILKP----VKKKKIK 80
            :::::..:.:...|...|.||.::.:|.|.|.:|.:| :..||....:.|:.:|    |..|:..
  Fly     6 TKKFYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTY 70

Human    81 REVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLY----------------QIL 129
            ||:::|::: ...|:|.|:| :..|.....:|       .:|:|:|                |.|
  Fly    71 RELRLLKHM-DHENVIGLLD-IFHPHPANGSL-------ENFQQVYLVTHLMDADLNNIIRMQHL 126

Human   130 TDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQ-EYNVRV 193
            :|..::|.:|::|:.|.|.||.|::|||:||.|:.: ::..:||::|:|||   .|.: |....|
  Fly   127 SDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAV-NEDCELRILDFGLA---RPTENEMTGYV 187

Human   194 ASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGY 258
            |:|:::.||:::::..||.::|:||:||::|.:|.|| ..|.|.|:..||..|.::|||... .:
  Fly   188 ATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRR-TLFPGTDHIHQLNLIMEMLGTPPA-EF 250

Human   259 LKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHP 323
            |||...:....:...|.....:.::|...:.|     |.|:|||:|:|..|.::|:||:||:.||
  Fly   251 LKKISSESARSYIQSLPPMKGRSFKNVFKNAN-----PLAIDLLEKMLELDAEKRITAEEALSHP 310

Human   324 YF----YPVVKEQSQP 335
            |.    .|.|::.|.|
  Fly   311 YLEKYAEPSVEQTSPP 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSNK2A2	NP_001887.1	STKc_CK2_alpha	22..326	CDD:271034	99/329 (30%)
p38a	NP_477163.1	STKc_p38	9..354	CDD:143356	103/338 (30%)