Protein Alignment CSNK2A2 and Cdk5

DIOPT Version :10

• Sequence 1: NP_001887.1
• Gene: CSNK2A2 / 1459
• HGNCID: 2459
• Length: 350
• Species: Homo sapiens
• Sequence 2: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Alignment Length: 307
• Identity: 103/307 - (33%)
• Similarity: 164/307 - (53%)
• Gaps: 45/307 - (14%)

Human    40 YQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVK--------KKKIKREVKILENLRGGTNII 96
            |..:.|:|.|.|..||:.   .|.:.:.:..||.|:        .....||:.:|:.|: ..||:
  Fly     4 YDKMEKIGEGTYGTVFKG---RNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELK-HKNIV 64

Human    97 KLIDTVKDPVSKTPALVFEYINNTDFKQLYQILT-DFDI---RFYMYELLKALDYCHSKGIMHRD 157
            :|||.:..  .|...||||:.:. |.|:.:..|. :.|:   |.:|.:||:.|.:|||..::|||
  Fly    65 RLIDVLHS--DKKLTLVFEHCDQ-DLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRD 126

Human   158 VKPHNVMIDHQQKKLRLIDWGLAE-FYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGC 221
            :||.|::| ::..:|:|.|:|||. |..|.:.|:..|.:.:::.|::|...::|..|:||||.||
  Fly   127 LKPQNLLI-NKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGC 190

Human   222 MLASMIFRREPFFHGQDNYDQLVRIAKVLGT--EELY---GYLKKYHIDLDPHFNDILGQHSRKR 281
            :||.:.....|.|.|.|..|||::|.:||||  |:.:   .:|..| :.| |.|..|..
  Fly   191 ILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDY-VAL-PSFPAITS------ 247

Human   282 WENFI---HSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
            |...:   :|:.|        |||.|||.....||::|:.||:||||
  Fly   248 WSQLVPRLNSKGR--------DLLQKLLICRPNQRISAEAAMQHPYF 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSNK2A2	NP_001887.1	STKc_CK2_alpha	22..326	CDD:271034	103/307 (34%)
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	101/305 (33%)