Protein Alignment CSNK2A2 and p38b

DIOPT Version :10

• Sequence 1: NP_001887.1
• Gene: CSNK2A2 / 1459
• HGNCID: 2459
• Length: 350
• Species: Homo sapiens
• Sequence 2: NP_477361.1
• Gene: p38b / 34780
• FlyBaseID: FBgn0024846
• Length: 365
• Species: Drosophila melanogaster
• Alignment Length: 359
• Identity: 100/359 - (27%)
• Similarity: 186/359 - (51%)
• Gaps: 67/359 - (18%)

Human    18 SLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEA-INITNNERVVVKILKP----VKKK 77
            |.:..:::..:.:...|...:.||.::.:|:|.|.:|.:| :..|:.:..:.|:.:|    |..|
  Fly     2 SRKMAKFYKLDINRTEWEIPETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAK 66

Human    78 KIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQI-------------- 128
            :..||:::|::: ...|:|.|:| |..|.....:|       ..|:|:|.:
  Fly    67 RTYRELRLLKHM-DHENVIGLLD-VFHPGQPADSL-------DQFQQVYMVTHLMDADLNNIIRT 122

Human   129 --LTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQ-EYN 190
              |:|..::|.:|::|:.|.|.||.|::|||:||.|:.: ::..:||::|:|||   .||: |..
  Fly   123 QKLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAV-NEDCELRILDFGLA---RPAESEMT 183

Human   191 VRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGT--- 252
            ..||:|:::.||:::::..|:.:.|:||:||::|.::..| ..|.|.|:..||..|.:||||
  Fly   184 GYVATRWYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGR-TLFPGTDHIHQLNLIMEVLGTPAD 247

Human   253 --------EELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYD 309
                    |....|::...:....:|.||.      |..|           |.|:|||:|:|..|
  Fly   248 EFMSRISSESARNYIRSLPVMPRRNFRDIF------RGAN-----------PLAIDLLEKMLELD 295

Human   310 HQQRLTAKEAMEHPY---FYPVVKEQSQPCADNA 340
            ..:|:||::|:.|||   ::....||:....|.:
  Fly   296 ADKRITAEQALAHPYMEKYHDPTDEQTAALYDQS 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSNK2A2	NP_001887.1	STKc_CK2_alpha	22..326	CDD:271034	96/339 (28%)
p38b	NP_477361.1	STKc_p38	8..353	CDD:143356	99/353 (28%)