Protein Alignment CSNK2A2 and kin-3

DIOPT Version :9

• Sequence 1: NP_001887.1
• Gene: CSNK2A2 / 1459
• HGNCID: 2459
• Length: 350
• Species: Homo sapiens
• Sequence 2: NP_492811.1
• Gene: kin-3 / 172978
• WormBaseID: WBGene00002191
• Length: 360
• Species: Caenorhabditis elegans
• Alignment Length: 331
• Identity: 262/331 - (79%)
• Similarity: 299/331 - (90%)
• Gaps: 0/331 - (0%)

Human     4 PAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINITNNERVVV 68
            |...||||||||||..|.|||||||||:..||..|||||||||||||||||||...::.:|:|||
 Worm     2 PPIPSRARVYAEVNPSRPREYWDYEAHMIEWGQIDDYQLVRKLGRGKYSEVFEGFKMSTDEKVVV 66

Human    69 KILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFD 133
            ||||||||||||||:|||||||||||||.|:|.||||:|:||||:||::||:|||||||.|:|:|
 Worm    67 KILKPVKKKKIKREIKILENLRGGTNIITLLDVVKDPISRTPALIFEHVNNSDFKQLYQTLSDYD 131

Human   134 IRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYF 198
            ||:|:||||||||:|||:|||||||||||||||.::::||||||||||||||.|:||||||||||
 Worm   132 IRYYLYELLKALDFCHSQGIMHRDVKPHNVMIDAEKRELRLIDWGLAEFYHPRQDYNVRVASRYF 196

Human   199 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYH 263
            ||||||||||.||||||||||||||||||||:||||||.|||||||||||||||:|||.|:.:||
 Worm   197 KGPELLVDYQCYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTDELYEYIARYH 261

Human   264 IDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPV 328
            |||||.||||||:|||||||.|||:||:|||:|||||.|||||||||.:||||:|||.|.||.||
 Worm   262 IDLDPRFNDILGRHSRKRWERFIHAENQHLVTPEALDFLDKLLRYDHAERLTAQEAMGHEYFRPV 326

Human   329 VKEQSQ 334
            |:..::
 Worm   327 VEAHAR 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSNK2A2	NP_001887.1	STKc_CK2_alpha	22..326	CDD:271034	246/303 (81%)
kin-3	NP_492811.1	STKc_CK2_alpha	19..323	CDD:271034	245/303 (81%)
		Pkinase	38..323	CDD:278497	232/284 (82%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C161448934
Domainoid	1	1.000	522	1.000	Domainoid score	I170
eggNOG	1	0.900	-	-		E1_KOG0668
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1098380at2759
OrthoFinder	1	1.000	-	-		FOG0000968
OrthoInspector	1	1.000	-	-		otm15578
orthoMCL	1	0.900	-	-		OOG6_100821
Panther	1	1.100	-	-	O	PTHR24054
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R250
SonicParanoid	1	1.000	-	-		X569
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.740