Protein Alignment Gfap and LamC

DIOPT Version :9

• Sequence 1: XP_030101431.1
• Gene: Gfap / 14580
• MGIID: 95697
• Length: 470
• Species: Mus musculus
• Sequence 2: NP_001260974.1
• Gene: LamC / 36615
• FlyBaseID: FBgn0010397
• Length: 640
• Species: Drosophila melanogaster
• Alignment Length: 522
• Identity: 151/522 - (28%)
• Similarity: 231/522 - (44%)
• Gaps: 101/522 - (19%)

Mouse     1 MERRRIT-SARRSYAS-ETVVRGLGPSRQLGTMPRFSLSRMTPPLPARVDFSLAGALNAGFKETR 63
            |..||:| :.|.|.|| .|.|.|...|.::|.        .:|..|.|.              :|
  Fly     1 MSARRVTLNTRVSRASTSTPVGGASTSSRVGA--------TSPTSPTRT--------------SR 43

Mouse    64 ASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLR---AKEPTKLADVYQAELRELRLRLD 125
            ..|:.|:..||||.|.||:::|.||.:|..|..|||..:   .:|.:.|..||:.||...|..||
  Fly    44 QQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLD 108

Mouse   126 QLTANSARLEVERDNFAQDLGTLRQKLQDETNLRLEAENNLAAY--------------------- 169
            :.....|:||::.....::...|:.:|..:|.....||||...|
  Fly   109 ETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADRKKF 173

Mouse   170 ---------------------RQEADEATLARVDLERKVESLEEEIQFLRKIYEEEVRELREQLA 213
                                 |::.:..||||||||.:.:||.||:.|..:::.:|:.|.|   :
  Fly   174 EDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETR---S 235

Mouse   214 QQQVHV-EMD-------VAKPDLTAALREIRTQYEAVATSNMQETEEWYRSKFADLTDAASRNAE 270
            ::|:.: |:|       .||  |..:|:|:|.|||.....|.:|.|..|.::..:|..||:|.|:
  Fly   236 RRQIEISEIDGRLSRQYEAK--LQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQ 298

Mouse   271 LLRQAKHEANDYRRQLQALTCDLESLRGTNESLERQMREQEERHARESASYQEALARLEEEGQSL 335
            ....|..|....|.::..|...|::|..||..|..::||.|.....|...:.:.:|.||.|.|.:
  Fly   299 GSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRM 363

Mouse   336 KEEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRGGKSTKEG---EG 397
            ::|||..|||||.|:::|::||:|||.|.|||.|||.|:        |::..|..:|..|   .|
  Fly   364 RDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRL--------NIESPGRPTTDSGISSNG 420

Mouse   398 QKVTRPLKRLTIQVVPIQAHQIENG-----ALPAAETSLDTKSVSEGHLKRNIVVKTVEMRDGEV 457
            ..:|......:.:|.|........|     |:....|.:|.   ||........|......|.|:
  Fly   421 SHLTASASSRSGRVTPSGRRSATPGISGSSAVKRRRTVIDE---SEDRTLSEYSVNAAAKGDLEI 482

Mouse   458 IK 459
            |:
  Fly   483 IE 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gfap	XP_030101431.1	Filament_head	4..63	CDD:368088	15/60 (25%)
		Filament	65..373	CDD:365827	115/360 (32%)
LamC	NP_001260974.1	Filament	45..401	CDD:278467	115/360 (32%)
		ATP-synt_B	<67..>142	CDD:304375	22/74 (30%)
		MreC	<178..>224	CDD:302802	14/45 (31%)
		LTD	473..574	CDD:279300	3/12 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910