Protein Alignment CSNK2A1 and CkIIalpha

DIOPT Version :10

• Sequence 1: NP_001886.1
• Gene: CSNK2A1 / 1457
• HGNCID: 2457
• Length: 391
• Species: Homo sapiens
• Sequence 2: NP_524918.1
• Gene: CkIIalpha / 48448
• FlyBaseID: FBgn0264492
• Length: 336
• Species: Drosophila melanogaster
• Alignment Length: 327
• Identity: 290/327 - (88%)
• Similarity: 309/327 - (94%)
• Gaps: 0/327 - (0%)

Human     5 VPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKI 69
            :||.||||||||.|:|.||||||::||:||||||||||||||||||||||||||||..||.||||
  Fly     3 LPSAARVYTDVNAHKPDEYWDYENYVVDWGNQDDYQLVRKLGRGKYSEVFEAINITTTEKCVVKI 67

Human    70 LKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIR 134
            ||||||||||||||||||||||.|||||..:|||||||||||:|||||||||||||||||||:||
  Fly    68 LKPVKKKKIKREIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDYEIR 132

Human   135 FYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKG 199
            :|::|:|||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||
  Fly   133 YYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKG 197

Human   200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIE 264
            |||||||||||||||||||||||||||||||||||||||||||||||||||||:||.|:|||||:
  Fly   198 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNID 262

Human   265 LDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 329
            |||||:|||.|||||||||||||:|||||||||||||||||||||..||||||||.||||..:|.
  Fly   263 LDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYFLPIVN 327

Human   330 DQ 331
            .|
  Fly   328 GQ 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSNK2A1	NP_001886.1	STKc_CK2_alpha	20..325	CDD:271034	276/304 (91%)
		Interaction with beta subunit. /evidence=ECO:0000250	36..41		4/4 (100%)
CkIIalpha	NP_524918.1	STKc_CK2_alpha	18..322	CDD:271034	275/303 (91%)