Protein Alignment CSNK2A1 and rl

DIOPT Version :10

• Sequence 1: NP_001886.1
• Gene: CSNK2A1 / 1457
• HGNCID: 2457
• Length: 391
• Species: Homo sapiens
• Sequence 2: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 297
• Identity: 92/297 - (30%)
• Similarity: 157/297 - (52%)
• Gaps: 33/297 - (11%)

Human    45 LGRGKYSEVFEAINITNNEKVVVKILKPVKK----KKIKREIKILENLRGGPNIITLADIVK-DP 104
            :|.|.|..|..|.:...|::|.:|.:.|.:.    ::..|||.||...: ..|||.:.||:: |.
  Fly    44 IGEGAYGMVVSADDTLTNQRVAIKKISPFEHQTYCQRTLREITILTRFK-HENIIDIRDILRVDS 107

Human   105 VSR-TPALVFEHVNNTDFKQLYQT--LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDH 166
            :.: ....:.:.:..||..:|.:|  |::..|.:::|:||:.|.|.||..::|||:||.|::: :
  Fly   108 IDQMRDVYIVQCLMETDLYKLLKTQRLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLL-N 171

Human   167 EHRKLRLIDWGLA-----EFYHPG--QEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLAS 224
            :...|::.|:|||     |..|.|  .||   ||:|:::.||::::.:.|..|:|:||:||:||.
  Fly   172 KTCDLKICDFGLARIADPEHDHTGFLTEY---VATRWYRAPEIMLNSKGYTKSIDIWSVGCILAE 233

Human   225 MIFRKEPFFHGHDNYDQLVRIAKVLGT---EDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVH 286
            |:..: |.|.|....|||..|..|||:   :||...|:    |....:.:.|.......|.:...
  Fly   234 MLSNR-PIFPGKHYLDQLNHILGVLGSPSRDDLECIIN----EKARNYLESLPFKPNVPWAKLFP 293

Human   287 SENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPY 323
            :     ....|||.|.|:|.::...|:...||:.|||
  Fly   294 N-----ADALALDLLGKMLTFNPHKRIPVEEALAHPY 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSNK2A1	NP_001886.1	STKc_CK2_alpha	20..325	CDD:271034	92/297 (31%)
		Interaction with beta subunit. /evidence=ECO:0000250	36..41
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	92/297 (31%)