Protein Alignment Gdf5 and scw

DIOPT Version :9

• Sequence 1: NP_032135.2
• Gene: Gdf5 / 14563
• MGIID: 95688
• Length: 495
• Species: Mus musculus
• Sequence 2: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Alignment Length: 389
• Identity: 102/389 - (26%)
• Similarity: 162/389 - (41%)
• Gaps: 52/389 - (13%)

Mouse   120 GQLPGGKASSKAGSAPSSFLLKKTREPGTPREPKEPFRPPPITPHEYMLSLYRTLSDADRKGGNS 184
            |..|..:|.....::.|.|||:...|....:||||...    ..|:..|.....:|:.||:
  Fly    49 GDRPRRQAEPNLHNSASKFLLEVYNEISEDQEPKEVLH----QRHKRSLDDDILISNEDRQ---- 105

Mouse   185 SVKLEAGLANTITSFIDKGQDDRGPAVRKQRYVFDISALEKD-GLLGAELRILRKKPLDVAKPAV 248
                |....|:|.:|..:.:.::..........|:.:.:..| .|:.|.|||. |:|..|.:.|.
  Fly   106 ----EIASCNSILTFSSRLKPEQLDNELDMHITFNTNDVPVDLSLVQAMLRIY-KQPSLVDRRAN 165

Mouse   249 PSSGRVAQLKLSSCPSGRQPAALLDVRSVPGLDGS-GWEVFDIWKLFRNFKNSAQLC----LELE 308
            .:.....:|      ..||..:...:.||...... ||..|::....|.:.::..|.    |.:.
  Fly   166 FTVSVYRKL------DNRQDFSYRILGSVNTTSSQRGWLEFNLTDTLRYWLHNKGLQRRNELRIS 224

Mouse   309 AWERGRAVDLRGLGFERTARQVHEKALFLVFGRTKKRDLFFNEIKARSGQDDKTVYEYLFSQRRK 373
            ..:...:....||...:.:|...|.  |:| |.....:|.....|.|..:|           ..|
  Fly   225 IGDSQLSTFAAGLVTPQASRTSLEP--FIV-GYFNGPELLVKIQKLRFKRD-----------LEK 275

Mouse   374 RRA--------PLANRQGKRPSKNLKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFP 430
            |||        |.......||.::    |.|....|:||::...:|:|||.::||:.|.|.|.||
  Fly   276 RRAGGGSPPPPPPPPVDLYRPPQS----CERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFP 336

Mouse   431 LRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGC 494
            |.:.:..||||::||||:...|. .|..|||||.|..|:||...:.:.:...:|:..|.:.|||
  Fly   337 LGTKMNATNHAIVQTLMHLKQPH-LPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gdf5	NP_032135.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..162		12/41 (29%)
		TGFb_propeptide	139..338	CDD:279078	43/204 (21%)
		TGFB	394..495	CDD:214556	41/101 (41%)
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	49/226 (22%)
		TGFB	300..400	CDD:214556	41/101 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810