Protein Alignment Gdf11 and scw

DIOPT Version :9

• Sequence 1: NP_034402.1
• Gene: Gdf11 / 14561
• MGIID: 1338027
• Length: 405
• Species: Mus musculus
• Sequence 2: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Alignment Length: 370
• Identity: 86/370 - (23%)
• Similarity: 136/370 - (36%)
• Gaps: 74/370 - (20%)

Mouse    86 RLKEAPNISREVVKQLLPKAPPLQQILD----LHDFQGDALQPEDFL---EEDEYHATTETVISM 143
            |.:..||:.....|.||.....:.:..:    ||.....:|. :|.|   |:.:..|:..::::.
  Fly    53 RRQAEPNLHNSASKFLLEVYNEISEDQEPKEVLHQRHKRSLD-DDILISNEDRQEIASCNSILTF 116

Mouse   144 AQETDPAVQTDGSPLCCHFHFSPK--VMFTKVLKAQLWVYLRP--VPRPATVYLQILRLKPLTGE 204
            :....|. |.| :.|..|..|:..  .:...:::|.|.:|.:|  |.|.|...:.:.|..
  Fly   117 SSRLKPE-QLD-NELDMHITFNTNDVPVDLSLVQAMLRIYKQPSLVDRRANFTVSVYRKL----- 174

Mouse   205 GTAGGGGGGRRHIRIRSL-KIELHSRSGHWQSIDFKQVLHSWFRQPQSNWGIE------INAFDP 262
                   ..|:....|.| .:...|....|...:....|..|..    |.|::      |:..|.
  Fly   175 -------DNRQDFSYRILGSVNTTSSQRGWLEFNLTDTLRYWLH----NKGLQRRNELRISIGDS 228

Mouse   263 SGTDLAV---------TSLGP-------GAEGLHPFMELRVLENTKRSRRNLGL-------DCDE 304
            ..:..|.         |||.|       |.|.|....:||...:.::.|...|.       ..|.
  Fly   229 QLSTFAAGLVTPQASRTSLEPFIVGYFNGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVDL 293

Mouse   305 HSSESRCCRYPLTVDF-EAFGWDWIIAPKRYKANYCSGQCEYMFMQKYPHT---------HLVQQ 359
            :.....|.|...|||| |....:|:||||:::|.:|.|.|.:....|...|         ||.|.
  Fly   294 YRPPQSCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQP 358

Mouse   360 ANPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGC 404
            ..|:    |||.||.:..|.:|.:.::..|...|....|...|||
  Fly   359 HLPK----PCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gdf11	NP_034402.1	TGFb_propeptide	59..283	CDD:279078	46/230 (20%)
		TGFB	311..405	CDD:214556	35/104 (34%)
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	43/219 (20%)
		TGFB	300..400	CDD:214556	35/104 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810