Protein Alignment Gdf10 and scw

DIOPT Version :10

• Sequence 1: NP_665684.2
• Gene: Gdf10 / 14560
• MGIID: 95684
• Length: 476
• Species: Mus musculus
• Sequence 2: NP_524863.3
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Alignment Length: 470
• Identity: 91/470 - (19%)
• Similarity: 155/470 - (32%)
• Gaps: 161/470 - (34%)

Mouse    48 GDRDSQQSPGDAAAALGPGAQDMVAIHMLRLYEKYNRRGAPP----------------------- 89
            |||..:|:.        |...:..:..:|.:|.:.:....|.
  Fly    49 GDRPRRQAE--------PNLHNSASKFLLEVYNEISEDQEPKEVLHQRHKRSLDDDILISNEDRQ 105

Mouse    90 --GGGNTVRSFRARL--EMIDQK-PVYF-FNLTSMQDSEMILTAAFHFYSEPPRWPRAREVFCKP 148
              ...|::.:|.:||  |.:|.: .::. ||...:.....::.|....|.:|....|.......
  Fly   106 EIASCNSILTFSSRLKPEQLDNELDMHITFNTNDVPVDLSLVQAMLRIYKQPSLVDRRANFTVS- 169

Mouse   149 RAKNASCRLLTPGLPARLHLIFRSLSQNTATQGLLRGAMALTPPPRGLWQAKDISSII------K 207
                                ::|.|.........:.|::..|...|| |...:::..:      |
  Fly   170 --------------------VYRKLDNRQDFSYRILGSVNTTSSQRG-WLEFNLTDTLRYWLHNK 213

Mouse   208 AARRDGELLLS---AQLDT---GEKDPGVPRPSSHMPYILVYANDLAISEPNSVAVSLQRYDPFP 266
            ..:|..||.:|   :||.|   |...|...|.|.. |:|:.|.|.      ..:.|.:|:.
  Fly   214 GLQRRNELRISIGDSQLSTFAAGLVTPQASRTSLE-PFIVGYFNG------PELLVKIQKL---- 267

Mouse   267 AGDFEPGAAPNSSADPRVRRAAQVSKPLQDNELPGLDERPAPALHAQNFHKHEFWSSPFRALKPR 331
                      ....|...|||...|.|            |.|             ..|....:|
  Fly   268 ----------RFKRDLEKRRAGGGSPP------------PPP-------------PPPVDLYRP- 296

Mouse   332 TGRKDRKKKDQDTFTAASSQVLDFDEKTMQKARRRQWDEPRVCSRRYLKVDFADIGWNEWIISPK 396
                                                   |:.|.|....|||.::..:.|:|:||
  Fly   297 ---------------------------------------PQSCERLNFTVDFKELHMHNWVIAPK 322

Mouse   397 SFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGIVPGIPEPCCVPDKMNSLGVL-FLDENRNA 460
            .|:||:|.|.|.||:...:..:|||.:|:::...  .|.:|:|||||..:.::.:| :|:|:...
  Fly   323 KFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLK--QPHLPKPCCVPTVLGAITILRYLNEDIID 385

Mouse   461 VLKVYPNMSVETCAC 475
            :.| |.....:.|.|
  Fly   386 LTK-YQKAVAKECGC 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gdf10	NP_665684.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..63		4/14 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	268..301		6/32 (19%)
		TGF_beta_GDF10	365..476	CDD:381664	36/112 (32%)
scw	NP_524863.3	TGFb_propeptide	39..254	CDD:480997	41/235 (17%)
		TGF_beta_BMP5_like	299..400	CDD:381639	35/104 (34%)