Protein Alignment Gdf10 and scw

DIOPT Version :9

• Sequence 1: NP_665684.2
• Gene: Gdf10 / 14560
• MGIID: 95684
• Length: 476
• Species: Mus musculus
• Sequence 2: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Alignment Length: 470
• Identity: 91/470 - (19%)
• Similarity: 155/470 - (32%)
• Gaps: 161/470 - (34%)

Mouse    48 GDRDSQQSPGDAAAALGPGAQDMVAIHMLRLYEKYNRRGAPP----------------------- 89
            |||..:|:.        |...:..:..:|.:|.:.:....|.
  Fly    49 GDRPRRQAE--------PNLHNSASKFLLEVYNEISEDQEPKEVLHQRHKRSLDDDILISNEDRQ 105

Mouse    90 --GGGNTVRSFRARL--EMIDQK-PVYF-FNLTSMQDSEMILTAAFHFYSEPPRWPRAREVFCKP 148
              ...|::.:|.:||  |.:|.: .::. ||...:.....::.|....|.:|....|.......
  Fly   106 EIASCNSILTFSSRLKPEQLDNELDMHITFNTNDVPVDLSLVQAMLRIYKQPSLVDRRANFTVS- 169

Mouse   149 RAKNASCRLLTPGLPARLHLIFRSLSQNTATQGLLRGAMALTPPPRGLWQAKDISSII------K 207
                                ::|.|.........:.|::..|...|| |...:::..:      |
  Fly   170 --------------------VYRKLDNRQDFSYRILGSVNTTSSQRG-WLEFNLTDTLRYWLHNK 213

Mouse   208 AARRDGELLLS---AQLDT---GEKDPGVPRPSSHMPYILVYANDLAISEPNSVAVSLQRYDPFP 266
            ..:|..||.:|   :||.|   |...|...|.|.. |:|:.|.|.      ..:.|.:|:.
  Fly   214 GLQRRNELRISIGDSQLSTFAAGLVTPQASRTSLE-PFIVGYFNG------PELLVKIQKL---- 267

Mouse   267 AGDFEPGAAPNSSADPRVRRAAQVSKPLQDNELPGLDERPAPALHAQNFHKHEFWSSPFRALKPR 331
                      ....|...|||...|.|            |.|             ..|....:|
  Fly   268 ----------RFKRDLEKRRAGGGSPP------------PPP-------------PPPVDLYRP- 296

Mouse   332 TGRKDRKKKDQDTFTAASSQVLDFDEKTMQKARRRQWDEPRVCSRRYLKVDFADIGWNEWIISPK 396
                                                   |:.|.|....|||.::..:.|:|:||
  Fly   297 ---------------------------------------PQSCERLNFTVDFKELHMHNWVIAPK 322

Mouse   397 SFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGIVPGIPEPCCVPDKMNSLGVL-FLDENRNA 460
            .|:||:|.|.|.||:...:..:|||.:|:::...  .|.:|:|||||..:.::.:| :|:|:...
  Fly   323 KFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLK--QPHLPKPCCVPTVLGAITILRYLNEDIID 385

Mouse   461 VLKVYPNMSVETCAC 475
            :.| |.....:.|.|
  Fly   386 LTK-YQKAVAKECGC 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gdf10	NP_665684.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..63		4/14 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	268..301		6/32 (19%)
		TGF_beta	372..475	CDD:278448	34/103 (33%)
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	41/235 (17%)
		TGFB	300..400	CDD:214556	35/103 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810