Protein Alignment CSNK1E and ball

DIOPT Version :10

• Sequence 1: NP_001885.1
• Gene: CSNK1E / 1454
• HGNCID: 2453
• Length: 416
• Species: Homo sapiens
• Sequence 2: NP_651508.1
• Gene: ball / 43228
• FlyBaseID: FBgn0027889
• Length: 599
• Species: Drosophila melanogaster
• Alignment Length: 488
• Identity: 122/488 - (25%)
• Similarity: 187/488 - (38%)
• Gaps: 101/488 - (20%)

Human     8 KYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFY----------KMMQ-- 60
            ::|:|..||.|.||:||....:......|: ::|....:..|.:|..||          :.||
  Fly    46 QWRIGPSIGVGGFGEIYAACKVGEKNYDAV-VKCEPHGNGPLFVEMHFYLRNAKLEDIKQFMQKH 109

Human    61 --GGVGIPSIKWCGA---EGD-YNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYI 119
              ..:|:|.|...|:   .|: :..:||...|..|........::....||..||.||:...:|:
  Fly   110 GLKSLGMPYILANGSVEVNGEKHRFIVMPRYGSDLTKFLEQNGKRLPEGTVYRLAIQMLDVYQYM 174

Human   120 HSKNFIHRDVKPDNFLMGLGKKGNL-VYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASIN 183
            ||..::|.|:|..|.|:||.|.|.. .|::|||||..:   .|....| ...|...||..|.|.:
  Fly   175 HSNGYVHADLKAANILLGLEKGGAAQAYLVDFGLASHF---VTGDFKP-DPKKMHNGTIEYTSRD 235

Human   184 THLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL----CKGY 244
            .|||: .:||.|||.|||.|:.:....|||...|......|.::..|..|....|.|    .||.
  Fly   236 AHLGV-PTRRADLEILGYNLIEWLGAELPWVTQKLLAVPPKVQKAKEAFMDNIGESLKTLFPKGV 299

Human   245 PSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM---------------LK 294
            |.....::.:...|..:.:|||...|..|.:...:.....:...|:.|               .|
  Fly   300 PPPIGDFMKYVSKLTHNQEPDYDKCRSWFSSALKQLKIPNNGDLDFKMKPQTSSNNNLSPPGTSK 364

Human   295 FGAARNPEDVD------------RERREHEREERMGQLRGSATRALP---------------PGP 332
            ...||..:.:|            ....:.|.||.....:.:|.:..|               ..|
  Fly   365 AATARKAKKIDSPVLNSSLDEKISASEDDEEEEEKSHRKKTAKKVTPSARNAKVSPLKRVADSSP 429

Human   333 PTGATANRLRSAAEPVASTPASRIQPAGNTSPRAISRVD---------RERKVSMRLH------- 381
            |     ::.|...|| .|||..|..|..:..||:..:..         |.|..:.:::
  Fly   430 P-----SQKRVKTEP-KSTPRERATPKASPKPRSTPKASPKPQTPTAARLRTPNAKINFSPSISL 488

Human   382 RGAPA--NVSSSDLTGRQEVSRIPASQTSVPFD 412
            ||.|.  .|.:.|||.:      |.|:.:..|:
  Fly   489 RGRPGGKTVINDDLTPQ------PRSKKTYEFN 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSNK1E	NP_001885.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	87/296 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	301..416		30/157 (19%)
ball	NP_651508.1	STKc_VRK	36..328	CDD:270917	86/287 (30%)
		PRK11633	<410..>471	CDD:236940	13/66 (20%)