Protein Alignment CSNK1E and CG7094

DIOPT Version :9

• Sequence 1: NP_001885.1
• Gene: CSNK1E / 1454
• HGNCID: 2453
• Length: 416
• Species: Homo sapiens
• Sequence 2: NP_609851.2
• Gene: CG7094 / 35065
• FlyBaseID: FBgn0032650
• Length: 390
• Species: Drosophila melanogaster
• Alignment Length: 408
• Identity: 195/408 - (47%)
• Similarity: 254/408 - (62%)
• Gaps: 59/408 - (14%)

Human     2 ELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIP 66
            :|.:|.||||.:.||||||||||||.:|..|.|||||:|....|:|||..|:|.|:.:....|.|
  Fly    20 KLLIGGKYRLVKPIGSGSFGDIYLGLSITDGSEVAIKVEKNDAKYPQLIYEAKVYEQLARCPGFP 84

Human    67 SIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKP 131
            ::...|.|.:||.|||:|||||||:|||.|.|:|||||||:|.||::.|||.:|.:.|||||:||
  Fly    85 TLLHYGCEKNYNAMVMDLLGPSLEELFNLCKRRFSLKTVLMLTDQLLMRIECVHERGFIHRDIKP 149

Human   132 DNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDL 196
            |||||||.:..|.:|:|||||:|:|:|..:..|||||.::|||||.||||||..:|:|||||||:
  Fly   150 DNFLMGLDRHCNKLYLIDFGLSKRYKDIESEIHIPYRTDRNLTGTVRYASINAQIGVEQSRRDDM 214

Human   197 ESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFD 261
            ||:.|.|||||||.|||||:.||.|:||||:|.|||.|..|..||||:||||...:.:.|:|.|.
  Fly   215 ESMSYCLMYFNLGKLPWQGITAANKKQKYEKILEKKTSVTIAQLCKGFPSEFCLLMTYVRNLGFK 279

Human   262 DKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARNPEDVDRERR---EHEREE---RMGQL 320
            :.||::||||:||.||......|||::||..|:    :..:.:.|.|.   |.||||   |.|:
  Fly   280 EPPDHTYLRQIFRILFRSLNHHYDYIYDWTALQ----QQKDQICRSREQILESEREEVRKRDGE- 339

Human   321 RGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAGNTSPRAISRVDRERKVSM---RLHR 382
            ||                      .||                     :.|:||...:   |||:
  Fly   340 RG----------------------CEP---------------------QRDKERHKDLELDRLHK 361

Human   383 GA--PANVSSSDLTGRQE 398
            .:  .|..|:..||.|.:
  Fly   362 TSTQQAKCSNGHLTNRYD 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSNK1E	NP_001885.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	163/273 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	301..416		24/109 (22%)
CG7094	NP_609851.2	STKc_CK1	26..291	CDD:270918	159/264 (60%)
		SPS1	26..>266	CDD:223589	148/239 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54222
OrthoDB	1	1.010	-	-		D1097975at2759
OrthoFinder	1	1.000	-	-		FOG0000297
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100396
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.730