Protein Alignment CSNK1D and dco

DIOPT Version :10

• Sequence 1: XP_005256393.1
• Gene: CSNK1D / 1453
• HGNCID: 2452
• Length: 450
• Species: Homo sapiens
• Sequence 2: NP_524602.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Alignment Length: 415
• Identity: 278/415 - (66%)
• Similarity: 313/415 - (75%)
• Gaps: 40/415 - (9%)

Human     1 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGI 65
            |||||||:|||||||||||||||||||.|..||||||||||::|||||||||||.||.||||:||
  Fly     1 MELRVGNKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGI 65

Human    66 PTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVK 130
            |.|.|||:|||||||||||||||||||||||||:|||||||||||||||||:||||::|||||:|
  Fly    66 PRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIK 130

Human   131 PDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDD 195
            |||||||||||||||||||||||||:||||:.:||||||||||||||||||||||||||||||||
  Fly   131 PDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDD 195

Human   196 LESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRF 260
            ||||||||||||||:|||||||||.||||||||||||:||.|.|||||:||||..||||||.:.|
  Fly   196 LESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHF 260

Human   261 DDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASR-------AADDAERE----------- 307
            |.:|||.:||:||||||||.||:||||||||:||||..|       |.|.|:.:
  Fly   261 DQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFGGPRNPQAIQQAQDGADGQAGHDAVAAAAA 325

Human   308 -----RRDREERLRHSRNPATRGLPSTA----------------SGRLRGTQEVAPPTPLTPTSH 351
                 .....::.:|..|.|..|...:|                :|...|:|.:.........|.
  Fly   326 VAAAAAASSHQQQQHKVNAALGGGGGSAAQQQLQGGQTLAMLGGNGGGNGSQLIGGNGLNMDDSM 390

Human   352 TANTSPRPVSGMERERKVSMRLHRG 376
            .|..|.||..... ||:.|:|:.:|
  Fly   391 AATNSSRPPYDTP-ERRPSIRMRQG 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSNK1D	XP_005256393.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	235/273 (86%)
dco	NP_524602.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	235/273 (86%)