Protein Alignment CSNK1D and CG12147

DIOPT Version :10

• Sequence 1: XP_005256393.1
• Gene: CSNK1D / 1453
• HGNCID: 2452
• Length: 450
• Species: Homo sapiens
• Sequence 2: NP_649536.1
• Gene: CG12147 / 40651
• FlyBaseID: FBgn0037325
• Length: 477
• Species: Drosophila melanogaster
• Alignment Length: 425
• Identity: 188/425 - (44%)
• Similarity: 255/425 - (60%)
• Gaps: 61/425 - (14%)

Human     2 ELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIP 66
            |:.|..:|||.::||:||||:::....:...|:||||||....|||.|..|::||.::|||:|||
  Fly    61 EIIVAGKYRLLKRIGNGSFGELFQAEGLKYHEKVAIKLESSTVKHPLLPREARIYGILQGGLGIP 125

Human    67 TIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKP 131
            .::....||.||||||:||||:||||.|.|||.||:||.|:||||:::|:|.:|.:.|||||:||
  Fly   126 HVKHYATEGAYNVMVMDLLGPTLEDLLNLCSRSFSMKTTLMLADQILARVELLHRRCFIHRDIKP 190

Human   132 DNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDL 196
            |||||||.:....||:||||||||:...||.:||.|.||::|.|||||||:..|.. ||||||||
  Fly   191 DNFLMGLNRHQTQVYMIDFGLAKKFYSLRTQKHIGYTENRDLVGTARYASVRAHYA-EQSRRDDL 254

Human   197 ESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFD 261
            ||:||:|:||..|.|||||::|.::.||||:|:|.|.:.|::.||.|.|.||..||.:||.|.|.
  Fly   255 ESVGYLLLYFQRGRLPWQGIRAQSQAQKYEKIAEYKANIPLQQLCSGLPVEFFMYLKYCRKLHFA 319

Human   262 DKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDR---------EERLRH 317
            :||||.||:|||:.||..|....|::|||.:||..:.......:...|||         :||.|:
  Fly   320 EKPDYVYLQQLFKVLFRNQYKVCDFLFDWVVLKRESPEQQSQQKGRERDRGGKRNVVVQKERHRN 384

Human   318 ---------------------SRNPATRG------LPSTASG------------RLRGTQEVAPP 343
                                 ..|.:|.|      .|....|            ||:.....||
  Fly   385 KDRDSDTQRCRIKNGGDLLEIEENESTTGEDPNEDKPQKKHGKACSCSYHLQKKRLQDRDRRAP- 448

Human   344 TPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAP 378
                     ..|..|.:|| |:|:::.:.| ||:|
  Fly   449 ---------LMTERRILSG-EQEQELELEL-RGSP 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSNK1D	XP_005256393.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	155/273 (57%)
CG12147	NP_649536.1	STKc_CK1	67..331	CDD:270918	150/264 (57%)