Protein Alignment CSNK1D and CkIalpha

DIOPT Version :9

• Sequence 1: XP_005256393.1
• Gene: CSNK1D / 1453
• HGNCID: 2452
• Length: 450
• Species: Homo sapiens
• Sequence 2: NP_001162737.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Alignment Length: 317
• Identity: 209/317 - (65%)
• Similarity: 255/317 - (80%)
• Gaps: 4/317 - (1%)

Human     2 ELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIP 66
            |:.||.:||:.||||||||||||||..|.:|||||||:|....:||||..|:|:|:::.||||.|
  Fly    13 EIIVGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGVGFP 77

Human    67 TIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKP 131
            .||..|.|.::|.:||:|||||||||||||:|.|::||||:|.||||.|:||||.|.|||||:||
  Fly    78 RIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKP 142

Human   132 DNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDL 196
            ||||||:|:..|.:::||||||||:||..|..||.|||:|||||||||||||.|||||||||||:
  Fly   143 DNFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSRRDDM 207

Human   197 ESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFD 261
            ||||||:||||.|.|||||:||.||:||||:||||||||||||||||.|:||:.|||:||||||:
  Fly   208 ESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPAEFSMYLNYCRSLRFE 272

Human   262 DKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK----FGASRAADDAERERRDREER 314
            ::|||.|||||||.||......|||::||.|||    .|....|...|:..:|:|::
  Fly   273 EQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLKQKTHQGQPNPAILLEQLDKDKEKQ 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSNK1D	XP_005256393.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	193/273 (71%)
		TyrKc	10..273	CDD:197581	187/262 (71%)
CkIalpha	NP_001162737.1	PKc_like	19..284	CDD:304357	188/264 (71%)
		Pkinase_Tyr	23..284	CDD:285015	186/260 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54222
OrthoDB	1	1.010	-	-		D1097975at2759
OrthoFinder	1	1.000	-	-		FOG0000297
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100396
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3408
SonicParanoid	1	1.000	-	-		X224
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.760